research The role of hair follicles in the percutaneous absorption of caffeine
Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
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research Hormone therapy for transgender patients
Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.
research Microneedles as the technique of drug delivery enhancement in diverse organs and tissues
Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
research Microneedle applications in improving skin appearance
Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.
research Smoking and the skin
Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
research Polycystic Ovarian Syndrome
Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research Venous and pulmonary thromboembolism and combined hormonal contraceptives. Systematic review and meta-analysis
Some birth control pills have a higher risk of blood clots than others.
research STEROIDS AND STEROID-LIKE COMPOUNDS
Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
research Combined hormonal contraception and venous thromboembolism
Birth control pills increase the risk of blood clots, especially within the first year and with certain types.
research Associations between transition‐specific stress experience, nocturnal decline in ambulatory blood pressure, and C‐reactive protein levels among transgender men
Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.
research Anabolic-androgenic steroids and cardiovascular risk
Using steroids can increase the risk of heart problems.
research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors
Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.
research Drug Delivery Applications of Three-Dimensional Printed (3DP) Mesoporous Scaffolds
3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.
research Androgen treatment of postmenopausal women
Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.
research Dermal papilla cells induce keratinocyte tubulogenesis in culture
Skin cells can help create early hair-like structures in lab cultures.
research Cognitive effects of testosterone and finasteride administration in older hypogonadal men.
Testosterone improves mood and thinking skills; finasteride has no effect.
research Applications of steroid drugs entrapped in cyclodextrins
Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
research Thiolated and PEGylated silica nanoparticle delivery to hair follicles
Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
research Effects of pre- and post-pubertal dihydrotestosterone treatment on penile length in 5α-reductase type 2 deficiency
Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.
research The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis
Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
research Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride
Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
research Testosterone Treatment in Women – An Overview
Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro
Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Ammonium bisulfite contact dermatitis: face eczema due to a bleaching ointment used during hair‐dying
Ammonium bisulfite in hair bleach can cause facial eczema.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
research Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase
New compounds were made that effectively block a specific enzyme related to androgen conditions.
research PCOS and Obesity: Contraception Challenges
Low-dose ethinyl estradiol and LNG-IUD are safer contraception options for obese women with PCOS.
research Maintenance of optimised hair growth from viable terminal scalp hair follicles at baseline with oral finasteride in male pattern hair loss and first evidence of a “drug dependency” and a post-finasteride “rebound effect”.
Finasteride helps hair growth but stopping it causes faster hair loss.