18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
January 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil alone is effective for treating hair loss, but combining it with dutasteride or finasteride may offer better results.
September 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
3 citations
,
December 2016 in “Universal journal of pharmaceutical research” Finasteride, a drug used for anti-hyperplasia, can be effectively delivered in the form of matrix tablets.
1 citations
,
August 2018 in “Journal of The American Academy of Dermatology” Dutasteride and minoxidil mesotherapy effectively treats hair loss with minimal side effects.
January 2018 in “Journal of analytical, bioanalytical and separation techniques” 4 citations
,
April 2020 in “Dermatology practical & conceptual” Topical finasteride works faster and better than 17α-estradiol for postmenopausal hair loss.
9 citations
,
January 2017 in “Farmacia” Finasteride can still be used for hair loss with careful consideration of side effects and patient information.
6 citations
,
October 2012 in “PubMed” The combined treatment of 3% minoxidil and 0.1% finasteride is more effective in improving hair loss than 3% minoxidil alone, with similar side effects.
June 2025 in “Journal of Cosmetic Dermatology” Dutasteride 0.5 mg/day is the most effective treatment for male pattern hair loss.
September 2020 in “Current Enzyme Inhibition” Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.
Low-dose oral minoxidil is safe and effective for treating hair loss, with most side effects being mild and reversible.
19 citations
,
July 2005 in “Steroids” Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.
January 2025 in “Journal of Drugs in Dermatology” Oral minoxidil is easier to use and more satisfying for hair loss treatment than topical minoxidil.
19 citations
,
May 2017 in “Dermatologic Surgery” Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.
11 citations
,
May 2010 in “Journal of Medicinal Chemistry” A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
Oral minoxidil affects prostate tissue but is less harmful than finasteride.
August 2019 in “Journal of The American Academy of Dermatology” 5% minoxidil foam effectively regrows hair in women, with postmenopausal women seeing the most improvement.
October 2018 in “IP Indian journal of clinical and experimental dermatology” Combining 5% minoxidil with PRP is better than PRP alone for treating male hair loss.
13 citations
,
January 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Minoxidil works faster and is more cost-effective for treating hair loss, but platelet-rich plasma microneedling can be an alternative for those who can't use minoxidil.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Current treatments can slow hair loss and promote regrowth, with hair transplantation being most effective for advanced cases.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Current treatments can slow hair loss and promote regrowth, with hair transplantation being most effective for advanced cases.
9 citations
,
January 2009 in “PubMed” Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
34 citations
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October 1994 in “Journal of Pharmaceutical Sciences” Ethanol over 50% helps minoxidil absorb better into skin.
October 2019 in “International Journal of Research in Dermatology” Combining minoxidil and spironolactone is more effective for female hair loss, but minoxidil alone is sufficient after 6 months.
5 citations
,
May 1994 in “Facial plastic surgery clinics of North America” Minoxidil was promising for treating male and female pattern baldness in 1994, but more research on genetics and other treatments was needed.
24 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil 1% and 2% best promote hair growth and may prevent hair loss.
23 citations
,
May 2019 in “Expert Opinion on Therapeutic Patents” New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
2 citations
,
January 2014 in “Journal of the American Academy of Dermatology” Topical minoxidil effectively promotes hair regrowth in male pattern baldness.
1 citations
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November 2020 in “Journal of The American Academy of Dermatology” PRP helps treat hair loss effectively with natural methods.