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Did you mean Matrix Metalloproteinases?

GlossaryMatrix Metalloproteinases

enzymes that degrade extracellular matrix proteins

Matrix Metalloproteinases (MMPs) are a group of enzymes that break down proteins in the extracellular matrix, which is the network of molecules surrounding cells. They play a crucial role in tissue remodeling, wound healing, and various physiological processes, but their overactivity can contribute to diseases like arthritis and cancer.

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research A polymorphism in the matrix metalloproteinase-1 gene promoter is associated with the presence of polycystic ovary syndrome in Caucasian women

8 citations , May 2005 in “Fertility and Sterility”

A specific gene variation is linked to a higher risk of polycystic ovary syndrome in Caucasian women.

research In-Vitro Anticancer Activity of Chemical Constituents from Etlingera alba Poulsen against Triple Negative Breast Cancer and in silico Approaches towards Matrix metalloproteinase-1 Inhibition

7 citations , May 2022 in “Indonesian Journal of Science and Technology”

Compounds from Etlingera alba may help treat Triple Negative Breast Cancer.

Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

3 citations , July 2020 in “Frontiers in Cell and Developmental Biology”

Vitexin Compound 1 may help reduce skin aging caused by UVA light.

research Oral Centella asiatica Extract Attenuates UVB-Induced Skin Photoaging via Antioxidant, Anti-Inflammatory, and Extracellular Matrix-Preserving Effects in Hairless Mice

December 2025 in “International Journal of Molecular Sciences”

Centella asiatica extract taken orally can reduce skin aging from UVB exposure.

Modulation of Photoaging-Induced Cutaneous Elastin: Evaluation of Gene and Protein Expression of Markers Related to Elastogenesis Under Different Photoexposure Conditions

research Modulation of Photoaging-Induced Cutaneous Elastin: Evaluation of Gene and Protein Expression of Markers Related to Elastogenesis Under Different Photoexposure Conditions

14 citations , October 2021 in “Dermatology and Therapy”

UV exposure accelerates skin aging by altering elastin, leading to wrinkles.

research Effects of autologous platelet‑rich plasma injections on facial skin rejuvenation

40 citations , February 2020 in “Experimental and Therapeutic Medicine”

PRP injections improve facial skin by reducing wrinkles and pores.

research Connective tissue sheath of hair follicle is a major source of dermal type I procollagen in human scalp

4 citations , September 2012 in “Journal of dermatological science”

The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.

research Inhibition of TNF-α-Induced Collagen Degradation and Oxidative Damage by Centipeda minima and Brevilin A in Human Dermal Fibroblasts

1 citations , May 2025 in “Current Issues in Molecular Biology”

Centipeda minima and brevilin A protect skin cells from damage and aging.

research Anti-aging effect of Grateloupia elata extract in skin

September 2025 in “Journal of Applied Biological Chemistry”

Grateloupia elata extract may be effective for anti-aging skincare.

research The effects of infrared radiation on the human skin

July 2023 in “Photodermatology, Photoimmunology and Photomedicine”

Infrared radiation can cause skin aging and cancer at high temperatures but may have therapeutic benefits at controlled levels.

research MON-203 Dermatological Effects Of Hormone Replacement Therapy

October 2025 in “Journal of the Endocrine Society”

Hormone Replacement Therapy improves skin health in postmenopausal women by boosting collagen and hydration.

research The Diameter Factor of Aligned Membranes Facilitates Cutaneous Wound Healing by Promoting Epithelialization in an Immune Way

1 citations , February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

A300 membranes help skin heal faster by promoting cell growth and repair.

research Expression Profiling and Cellular Localization of Genes Associated with the Hair Cycle Induced by Wax Depilation

27 citations , August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

Researchers found new genes involved in hair growth, which could help develop new hair treatments.

research Scarless wound healing: Transitioning from fetal research to regenerative healing

79 citations , January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology”

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

Identifying Key Components and Therapeutic Targets of the Immune System in Hidradenitis Suppurativa with an Emphasis on Neutrophils

research Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils

16 citations , September 2020 in “British journal of dermatology/British journal of dermatology, Supplement”

The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

research Antioxidant Capacity and Protective Effect of Cow Placenta Extract on D-Galactose-Induced Skin Aging in Mice

4 citations , November 2022 in “Nutrients”

Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.

iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration

research iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration

19 citations , December 2016 in “PLOS ONE”

Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.

Cthrc1 Deficiency Aggravates Wound Healing and Promotes Cardiac Rupture After Myocardial Infarction via Non-Canonical WNT5A Signaling Pathway

research Cthrc1 deficiency aggravates wound healing and promotes cardiac rupture after myocardial infarction via non-canonical WNT5A signaling pathway

9 citations , January 2023 in “International Journal of Biological Sciences”

CTHRC1 is essential for healing and preventing heart rupture after a heart attack.

research In Vivo Evaluation ofEclipta albaExtract as Anticancer and Multidrug Resistance Reversal Agent

9 citations , June 2014 in “Nutrition and Cancer”

Eclipta alba extract may work as an anticancer agent and help reverse drug resistance.

research Matrisomal components involved in regenerative wound healing in axolotl and Acomys: implications for biomaterial development

January 2023 in “Biomaterials Science”

Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.

research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection

133 citations , May 2016 in “Cell Host & Microbe”

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

research Ameliorative effect of tranexamic acid on physiological skin aging and its sex difference in mice

13 citations , May 2019 in “Archives of dermatological research”

Tranexamic acid reduces skin aging more in female mice.

research 13. Wound Healing & Hair

April 2003 in “Journal of Cutaneous Medicine and Surgery”

Some treatments work better for different types of hair loss, and nutrients like iron and L-lysine are important for preventing hair loss.

research Biological activities supporting development of cosmeceutical skin products from Wedelia trilobata (L.) Hitch. flower extract

3 citations , January 2023 in “Agriculture and Natural Resources”

Wedelia trilobata flower extract could be a valuable ingredient for skin care products due to its antioxidant, antimicrobial, and anti-inflammatory properties.

research Referee report. For: Molecular mediators involved in skin healing: a narrative review [version 1; peer review: 1 approved with reservations]

January 2022 in “Faculty of 1000 Research Ltd”

Understanding molecular mediators can improve skin healing treatments.

research New treatments for rheumatoid arthritis

13 citations , January 1999 in “Postgraduate Medicine”

New drugs for rheumatoid arthritis show improvement but have side effects and are not a cure.