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A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

Loss of Ten1 in mice causes telomere shortening and symptoms similar to human dyskeratosis congenita.

Retinoic acid causes gland formation instead of hair in mouse skin by altering epidermal and dermal interactions.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

Increasing calcium sensing receptor speeds up skin and hair development in mice.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.

Dimethylarsinic acid speeds up skin tumor growth in certain mice.

Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.

ErbB2 signaling is crucial for skin cell growth and cancer development in mice.

Agouti and AGRP affect pigmentation and obesity, with implications for metabolic disorders.

ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.

Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.

A new genetic mutation in the TRPS1 gene causes Trichorhinophalangeal Syndrome, leading to specific hair, dental, and bone issues.

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

A vitamin D receptor mutation causes rickets and affects immune responses.

Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

cDermo-1 causes dense skin, feathers, and scales in chickens.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Injury boosts normal skin cell growth, reducing cancer cell advantage.

MITF+ melanoma patients are more likely to have multiple melanomas and unique skin patterns.

Higher CRBP1 levels are linked to more severe alopecia areata.

The MDR1 C3435T polymorphism does not significantly affect methotrexate response in rheumatoid arthritis patients.

Human basal cell carcinomas and squamous cell carcinomas have unique gene expression patterns not fully mirrored in mouse models.

New mutations in the VDR gene cause vitamin D-resistant rickets without hair loss.

HOXC13 is crucial for regulating hair keratin genes in hair follicles.

Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.