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research Antioxidant Activities of Natural Polysaccharides and Their Derivatives for Biomedical and Medicinal Applications

130 citations , December 2022 in “Antioxidants”

Natural polysaccharides have strong antioxidant properties that help fight diseases like Alzheimer's, diabetes, and heart disease.

research K6irs1, K6irs2, K6irs3, and K6irs4 Represent the Inner-Root-Sheath-Specific Type II Epithelial Keratins of the Human Hair Follicle1

130 citations , April 2003 in “Journal of Investigative Dermatology”

Four specific keratins in hair follicles help understand hair structure and function.

research Epidermal stem cells in wound healing and their clinical applications

129 citations , July 2019 in “Stem Cell Research & Therapy”

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

research Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome

119 citations , November 2016 in “American journal of human genetics”

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

research Human hair keratin and its-based biomaterials for biomedical applications

115 citations , August 2014 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine”

Human hair keratin can be used in many medical applications.

research Ultrasound-assisted extraction and analysis of maidenhairtree polysaccharides

111 citations , April 2023 in “Ultrasonics Sonochemistry”

Ultrasound helps efficiently extract beneficial compounds from maidenhairtree for potential medicinal use.

research A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity

98 citations , December 2015 in “The Journal of Cell Biology”

Keratin is crucial for skin barrier formation and affects mitochondrial function.

research Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases

97 citations , May 2019 in “Frontiers in Cell and Developmental Biology”

Abnormal ECM and immune cell interactions can cause skin diseases.

research Advances in Chitosan-Based Nanoparticles for Drug Delivery

96 citations , September 2021 in “International Journal of Molecular Sciences”

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

research Do nanoparticles have a future in dermal drug delivery?

87 citations , September 2016 in “Journal of Controlled Release”

Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.

research A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations and Applications

86 citations , August 2021 in “Polymers”

Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.

research Prevention and management of dermatological toxicities related to anticancer agents: ESMO Clinical Practice Guidelines☆

86 citations , November 2020 in “Annals of Oncology”

Early intervention and tailored management can reduce skin side effects from cancer treatments.

research Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes

86 citations , April 2009 in “Journal of anatomy”

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

research Design and fabrication of customizable microneedles enabled by 3D printing for biomedical applications

81 citations , October 2023 in “Bioactive Materials”

3D-printed microneedles improve drug delivery and diagnostics but face scalability and regulatory challenges.

research Insights into the angiogenic effects of nanomaterials: mechanisms involved and potential applications

80 citations , January 2020 in “Journal of Nanobiotechnology”

Nanomaterials can aid tissue repair and healing but need more safety research.

research Hydrogel-Based Skin Regeneration

76 citations , February 2024 in “International Journal of Molecular Sciences”

Hydrogels show promise for improving skin wound healing.

research The emerging progress on wound dressings and their application in clinic wound management

69 citations , November 2023 in “Heliyon”

Future wound dressings will be smart, multifunctional, and improve personalized medicine.

research Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages

68 citations , April 2014 in “Journal of Investigative Dermatology”

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.

research Tannic acid-functionalized 3D porous nanofiber sponge for antibiotic-free wound healing with enhanced hemostasis, antibacterial, and antioxidant properties

63 citations , June 2023 in “Journal of Nanobiotechnology”

The sponge heals wounds without antibiotics and has strong antibacterial and antioxidant properties.

research Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles

60 citations , December 2020 in “Stem Cell Research & Therapy”

ASC-CM is more effective than EV for treating osteoarthritis.

research Radiosensitization and Radioprotection by Curcumin in Glioblastoma and Other Cancers

57 citations , January 2022 in “Biomedicines”

Curcumin may improve cancer radiotherapy by making cancer cells more sensitive to radiation and protecting normal cells.

research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument

53 citations , January 2013 in “Journal of toxicologic pathology”

The project created a standardized system for classifying skin lesions in lab rats and mice.

research Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

52 citations , February 2012 in “PloS one”

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.

research Engineered extracellular vesicles for tissue repair and regeneration

51 citations , January 2024 in “Burns & Trauma”

Engineered extracellular vesicles can improve tissue repair and regeneration.

research The palette of techniques for cell cycle analysis

50 citations , May 2020 in “FEBS Letters”

New techniques improve understanding of cell cycle dynamics at the single-cell level.

research Lysophospholipid Mediators in Health and Disease

49 citations , November 2021 in “Annual review of pathology”

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

research Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges

48 citations , January 2018 in “Stem Cells International”

Skin-derived stem cells show promise for improving wound healing and creating transplantable tissue.

research Smart Microneedles for Therapy and Diagnosis

46 citations , January 2020 in “Research”

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

research
Novel Clove Essential Oil Nanoemulgel Tailored by Taguchi’s Model and Scaffold-Based Nanofibers: Phytopharmaceuticals with Promising Potential as Cyclooxygenase-2 Inhibitors in External Inflammation

45 citations , March 2020 in “International Journal of Nanomedicine”

Clove essential oil nanoemulgel effectively reduces skin inflammation and is a promising alternative to traditional anti-inflammatory drugs.

research The structure of the cornified claw sheath in the domesticated cat (Felis catus): implications for the claw‐shedding mechanism and the evolution of cornified digital end organs

45 citations , April 2009 in “Journal of anatomy”

Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.

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