research Effects of 5-alpha reductase inhibitors
5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
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research Valproic acid and alopecia: A two-edged sword
Valproic acid can cause hair loss when taken orally but may promote hair growth when applied topically.
research Fructose-1,6-bisphosphate aldolase A levels decrease in hair keratinocytes during androgenetic alopecia
ALDOA levels drop in hair cells during hair loss.
research Therapeutic potential and pharmacological insights of total glucosides of paeony in dermatologic diseases: a comprehensive review
Total glucosides of paeony can help treat skin conditions but need more research for clinical use.
research The role of zinc in skin physiology – relevance for the pathogenesis and treatment of vitiligo
Zinc may be linked to vitiligo development and severity, but its role is not fully understood and zinc supplementation benefits are unclear.
research Microneedles-A new paradigm in transdermal delivery of therapeutic agents
Microneedles offer a painless, effective way to deliver drugs through the skin.
research Skin Tissue: A Place for SARS-CoV-2 to Multiply and Transmit?
SARS-CoV-2 might infect and multiply in skin tissue, possibly aiding in its transmission.
research Alopecia and Clinical Presentation of Endocrinopathies: Pathogenetic and Diagnostic Aspects
Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.
research WARFARIN-INDUCED ALOPECIA: A RARE CASE REPORT
Warfarin can rarely cause hair loss, which is usually reversible.
research The Impact of the 5α-Reductase Inhibitors (5α-RIs) on Male Sexual Function and Psychological Well-Being
5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
research FORMULATION AND EVALUATION OF CONTROLLED RELEASE MATRIX TABLETS OF FINASTERIDE
The F9 formulation of Finasteride tablets, using Eudragit, successfully controlled drug release.
research Follicles, fungi and scalp conditions
Malassezia yeast plays a key role in dandruff and seborrhoeic dermatitis.
research Hair Loss in Patients on Glucagon-Like Peptide 1 Receptor Agonists: Understanding Risks and Managing Outcomes
Glucagon-like peptide 1 receptor agonists (GLP-1RAs), used for type 2 diabetes and weight loss, have been linked to hair loss, particularly with semaglutide and tirzepatide, though causality is not established. Evidence primarily comes from pharmacovigilance databases and retrospective studies, with no prospective, controlled studies specifically addressing this issue. Rapid weight loss from these drugs may cause telogen effluvium, a potential mechanism for hair loss. As prescriptions rise in Europe, cases may increase, necessitating further research into causality and risk factors. Clinicians should inform and monitor patients for potential hair loss.
research Updates on Trichodysplasia Spinulosa Disease
Trichodysplasia spinulosa is a rare skin condition linked to weakened immune systems, mostly in organ transplant patients.
research Signal Detection of Depression and Suicidality Associated with Finasteride and Dutasteride: Updated Pharmacovigilance Evidence and Recommendations for Comprehensive Psychiatric Assessment
Finasteride may cause depression and suicidal thoughts, especially in young men.
research The Risk of Benign Prostatic Hyperplasia and Prostate Cancer With Long-Term, Low Dose Finasteride Use in Adult Men with Nonscarring Alopecia: A Propensity-Matched Observational Study
Long-term, low-dose finasteride may reduce the risk of benign prostatic hyperplasia and prostate cancer.
research Case Report: Pulsed electric field treatment of metastatic liver disease demonstrating a possible abscopal response
Pulsed electric field treatment may help the immune system fight liver tumors.
research The brain–gut–skin axis in inflammatory and disfiguring skin diseases: mechanistic insights, clinical correlations, and therapeutic strategies
Skin diseases like acne and psoriasis are linked to stress, gut health, and inflammation, with new treatments focusing on gut and mind-body approaches.
research What “regenerative” means in aesthetic medicine: a narrative literature review attempting to demystify the core essence of regenerative aesthetics
Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
research Ca 2+ -mediated protein citrullination regulates proliferation in the regenerating and malignant CNS
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
research Topical Cetirizine in Androgenetic Alopecia: A Preliminary Study
Topical cetirizine may help increase hair count in androgenetic alopecia.
research Advancements in Bioactive Compounds and Therapeutic Agents for Alopecia: Trends and Future Perspectives
New treatments for alopecia show promise in restoring hair growth by targeting immune and hormonal factors.
research Tuning Scaffold Properties of New 1,4-Substituted Pyrrolo[3,2-c]quinoline Derivatives Endowed with Anticancer Potential, New Biological and In Silico Insights
Compound 7p shows strong potential as an anticancer agent.
research Cutaneous Adverse Effects of EGFR Therapy in Breast Cancer Treatment
EGFR inhibitors in breast cancer treatment can cause serious skin issues affecting patient quality of life.
research Rebamipide Induces Hair Regeneration Through EP4-Driven Lipid Metabolism Remodeling
Rebamipide may help regrow hair by activating hair follicle stem cells.
research MON-203 Dermatological Effects Of Hormone Replacement Therapy
Hormone Replacement Therapy improves skin health in postmenopausal women by boosting collagen and hydration.
research Quercetin Nanocrystal Gel: A Novel Topical Therapeutic Strategy for Androgenetic Alopecia
Quercetin nanocrystal gel shows promise for hair regrowth in androgenetic alopecia.
research In vitro anti-melanoma activity and in vivo hair growth stimulation by Lophocereus marginatus methanol extracts
Lophocereus marginatus extracts may help treat melanoma and stimulate hair growth.
research A Comprehensive Review on The Phytochemical Profile, Ethnobotanical Uses and Pharmacological Activities of Cuscuta Reflexa Roxb.: An Asiatic Parasitic Vine
Cuscuta reflexa has potential medicinal benefits but needs more research for clinical use.
research AcD : A Novel Bioactive Polymer Scaffold of Adipose‐Derived Stem Cells Combining With Decellularized Extracellular Matrix in Tissue Engineering
AcD scaffolds improve tissue repair and regeneration by combining stem cells with a supportive matrix.