research Transcriptomic Analysis Provides Molecular Insights into Skin Development in Dezhou Donkey Foals
Skin maturation in Dezhou donkey foals involves better barrier function, hair growth, and less collagen production.
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90-120 / 1000+ resultsresearch Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors
Hedgehog pathway inhibitors could be effective in treating melanoma.
research Hair regeneration: Mechano-activation and related therapeutic approaches.
Mechanical stimulation and new therapies show promise for hair regrowth.
research Mechanistic Insights on Dyspepsia Modulation by Salvia rosmarinus Through Network Pharmacology, Molecular Docking, and Molecular Dynamics
Rosemary may help reduce dyspepsia and gastric cancer risk.
research Progress on mitochondria and hair follicle development in androgenetic alopecia: relationships and therapeutic perspectives
Maintaining healthy mitochondria may help treat hair loss.
research Calcium channel inhibitor and extracellular calcium improve aminoglycoside-induced hair cell loss in zebrafish
Certain substances can protect against ear damage from some antibiotics in zebrafish.
research MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation
Tiny particles from stem cells can help protect ear cells from antibiotic damage by helping cells remove damaged parts.
research Scarless wound healing: Transitioning from fetal research to regenerative healing
Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging
Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
research Deciphering the molecular drivers for cashmere/pashmina fiber production in goats: a comprehensive review
research Novel Technologies for Exploring the Skin–Brain Axis
Advanced technologies can improve understanding and monitoring of skin-brain interactions.
research The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties
Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.
research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis
GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
research Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation
Understanding how certain proteins and genetic changes control skin stem cells is key to treating skin diseases.
research Integrin signalling regulates YAP/TAZ to control skin homeostasis
YAP and TAZ are crucial for skin cell growth and repair.
research Skin-type-dependent development of murine mechanosensory neurons
Mechanosensory neurons adapt to different skin types after birth.
research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons
Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
research Modulating mechanosensory afferent excitability by an atypical mG luR
A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
research Mechanical stimulation of human hair follicle outer root sheath cultures activates adjacent sensory neurons
Touching hair can activate nearby nerve cells through signals from the hair's outer layer.
research 161 Botanical extract effectiveness on overall well-being and well-aging. An in-vivo study
Botanical extract improved well-being and skin health in a test group compared to a placebo.
research Author response: Hair follicle epidermal stem cells define a niche for tactile sensation
Skin stem cells in hair follicles are important for touch sensation.
research Localization of mechanosensitive channel TRPV4 in mouse skin
TRPV4 helps sense pressure in mouse skin.
research 869 The specification of Merkel cell in the back skin and glabrous paw skin is controlled by FGFR2-meditated signaling
FGFR2 signaling controls Merkel cell formation in different skin regions.
research Localization of Merkel cells at hairless and hairy human skin sites using keratin 18
Merkel cells are more densely found in hairless skin areas like palms and soles.
research Three-dimensional microanatomy of mechanoreceptors and their possible mechanism of sensory transduction.
Mechanoreceptors convert physical touch into electrical signals through specialized nerve structures.
research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
research TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons
TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
research Author Response: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.