research A transient dermal niche and dual epidermal programs underlie sweat gland development
Sweat gland development involves two unique skin cell programs and a temporary skin environment.
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450-480 / 1000+ results research 896 Androgens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line
Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.
research A simple immunofluorescence technique for simultaneous visualization of mast cells and nerve fibers reveals selectivity and hair cycle - dependent changes in mast cell - nerve fiber contacts in murine skin
Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.
research Hypertrichosis of the eyelashes caused by bimatoprost
Bimatoprost can cause excessive eyelash growth.
research K31 as a novel marker for clear secretory cells in human eccrine sweat glands
K31 can identify clear secretory cells in human sweat glands.
research Pseudo Pemphigus Phenotypes in Mice with Inactivated Desmoglein 3
Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.
research Preparation of 4-aryl-2-trifluoromethylbenzonitrile derivatives as androgen receptor antagonists for topical suppression of sebum production
Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
research Basal Lamina Changes During Tissue Interactions in Hair Follicles—An In Vitro Study of Normal Dermal Papillae and Vitamin A-Induced Glandular Morphogenesis
research Eruptive vellus hair cysts of the labia majora: detection of openings of the cysts to the epidermis by dermoscopy
Dermoscopy can non-invasively detect eruptive vellus hair cysts on the labia majora.
research Treatment of Benign Essential Blepharospasm With Finasteride
Finasteride helps treat eyelid spasms.
research Sweat under surveillance: Loss of immune–metabolic loop during aging
Aging weakens sweat glands due to reduced support from immune cells, but treatments may help restore function.
research Hair follicles modulate skin barrier function
Hair follicles play a crucial role in regulating skin barrier function.
research Vesicle Formation and Follicular Root Sheath Separation in Mice Homozygous for Deleterious Alleles at the Balding (bal) Locus
A mutation in mice causes hair loss and skin issues due to a defect in a gene affecting cell adhesion.
research Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide-osmium tetroxide technique
Methylene blue staining effectively highlights detailed nerve structures in rat fur.
research Generalized trichoepitheliomas with alopecia and myasthenia gravis: Clinicopathologic and immunohistochemical study and comparison with classic and desmoplastic trichoepithelioma
Generalized trichoepitheliomas with hair loss may indicate myasthenia gravis.
research Anatomical Mapping and Density of Merkel Cells in Skin and Mucosae of the Dog
Dogs have varying numbers of touch-sensitive Merkel cells in different skin areas, with most in the oral mucosa and facial skin, unrelated to age, sex, breed, or color.
research Epidermal Barrier
Healthy skin prevents water loss and protects against threats.
research Skin and Adnexa of the Laboratory Mouse
research Is seborrhea a sign of autonomic impairment in Parkinson's disease?
Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
research 664 Understanding the pathogenesis of seborrhea-like dermatitis in the Mpzl3 knockout mice
ZNF750 and MPZL3 are important in causing seborrheic dermatitis.
research Eyelid Pilomatrixomas: A Case Report and Comprehensive Literature Review
Eyelid pilomatrixomas are rare, benign tumors that need accurate diagnosis for proper treatment.
research 1301 STIM1, but not STIM2, is the calcium sensor critical for sweat secretion
STIM1 is essential for sweat secretion.
research Acquired trichomegaly of the eyelashes and hypertrichosis induced by bimatoprost
Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.
research Pilomatricoma in the infraorbital region
Pilomatricoma is a rare, benign skin tumor that requires surgical removal for best results.
research Joint Public Review: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
Meis2 is essential for touch sensation and nerve function in mice.
research Pantolactams as androgen receptor antagonists for the topical suppression of sebum production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research Moist exposed burn ointment accelerates diabetes-related wound healing by promoting re-epithelialization
Moist Exposed Burn Ointment speeds up healing of diabetic wounds.
research Association of Corrugator Supercilii and Procerus Myectomy With Endoscopic Browlift Outcomes
Removing certain muscles during a browlift reduces glabellar wrinkles better long-term.
research A productive black facial pore. Trichofolliculoma
A black pore on a man's cheek was a hair follicle tumor and was removed.
research 260 Establishment and characterization of human sebocytic progenitor cells that can differentiate into functional sebocytes
Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.