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Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Multiple mouse desmoglein 1 isoforms have distinct roles in skin and hair development.

BMAL1 controls skin cell growth and UV damage risk, peaking at night.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

PP2Acα is essential for proper hair and skin development.

Peimine helps heal skin wounds by activating a specific cell signaling pathway.

Histone demethylases can change gene expression and may be linked to diseases like cancer.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.

Mouse hair keratins mHa1 and mHb4 can't form a strong network on their own in cells.

PINCH-1 is crucial for skin cell adhesion and movement, working with EPLIN and ILK.

Alk1 in specific cells is crucial for proper nerve branching and hair function.

AP-1 controls tumor cell type by affecting key signaling pathways.

BMI1 is essential for preventing hair greying and maintaining hair color.

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

MMP-9 is essential for proper hair canal formation.

Lysosomal proteases and cytoplasmic enzymes help hair follicle cells develop and differentiate.

CPK1 helps root hair growth in Arabidopsis by activating channels for calcium signaling.

Mf-rich hair degrades more than Ma-rich hair, especially with Proteinase K.

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.

Researchers found a new mutation in the FERMT1 gene in a Spanish family with Kindler syndrome.

The PIP5K1A gene helps cashmere growth in goats by promoting cell proliferation, and melatonin boosts its expression.

Melatonin may help whisker growth in mice.

Meis2 is essential for whisker development, independent of nerve involvement.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Engineered vesicles from macrophages help hair growth in mice and humans.

Tet2 and Tet3 enzymes are essential for controlling hair growth by affecting DNA demethylation and gene expression in mice.

Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.

Mdm2 is crucial for controlling p53 to maintain healthy cells and prevent tumors.