4 citations
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October 2021 in “International Journal of Cosmetic Science” Cirsium japonicum flower extract increases melanin production and could help treat depigmentation conditions.
4 citations
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July 2019 in “Clinics in Dermatology” The document concludes that while white skin, nail, and mucosa diseases increase skin cancer risk, they are generally harmless, especially compared to darker pigmentation conditions.
4 citations
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August 2016 in “PubMed” Repeated dyeing and shampooing cause hair color loss and damage.
4 citations
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April 1999 in “Dermatologic Clinics” Long-pulsed ruby lasers effectively reduce hair for up to 2 years with minimal pain.
4 citations
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February 2025 in “Pharmaceuticals” Voglibose may help treat skin hyperpigmentation safely.
3 citations
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November 2023 in “Frontiers in cell and developmental biology” Melanocytes are important for skin and hair color and protect the skin from UV damage.
3 citations
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January 2011 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” Male mice have thicker skin, causing more light scattering than females.
3 citations
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September 2023 in “Stem Cell Research & Therapy” Stem cells can be used to create long-lasting skin cells for treating pigment disorders.
3 citations
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May 2020 in “Acta pharmaceutica” Protocatechuic acid can reduce melanin production and boost antioxidant activity in hair follicles.
3 citations
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March 2019 in “Acta histochemica” Angiotensin II is found at higher levels in black sheep skin and may influence coat color.
3 citations
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January 2004 in “Journal of Wildlife Diseases” A deer fawn in South Dakota was the first cervid found with congenital hypotrichosis, a condition causing sparse or missing hair.
2 citations
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April 2025 in “Frontiers in Genetics” The ASIP gene is crucial for determining cattle coat color.
2 citations
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March 2023 in “JAAD case reports” Hair repigmentation can indicate malignancy and should be investigated.
2 citations
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October 2022 in “Jikken Dobutsu” Philippines stingless bee propolis helps hair grow by activating a specific cell signaling pathway.
2 citations
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September 2022 The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.
2 citations
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June 2020 in “Journal of Investigative Dermatology” 3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
2 citations
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January 2018 in “The Korea Journal of Herbology” A herbal extract can boost hair growth and pigmentation like minoxidil.
2 citations
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January 1973 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” Brown skin in guinea pigs has more ascorbic acid and related enzymes, black skin uses ascorbic acid well, and white skin has the most protein.
2 citations
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May 2023 in “Photobiomodulation, photomedicine, and laser surgery” Light therapy is effective and safe for treating skin color disorders like vitiligo and dark spots.
2 citations
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January 2020 in “BioMed Research International” Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
2 citations
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September 2009 in “Pigment Cell & Melanoma Research” Melanocytes in different body areas have evolved to perform specific functions based on their location.
1 citations
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July 2025 in “Journal of Cosmetic Dermatology” Lip aging differs from facial aging, needing specific care for barrier, wrinkles, and pigment changes.
1 citations
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June 2025 in “Journal of Cellular and Molecular Medicine” Plant-derived compounds may help reverse grey hair by boosting melanin production.
1 citations
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February 2025 in “Photodermatology Photoimmunology & Photomedicine” 830 nm LED light effectively treats and prevents skin redness and dark spots, while 590 nm LED light only helps prevent them.
1 citations
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December 2024 in “Case Reports in Dermatology” Cyclophosphamide likely causes skin darkening by affecting hair follicles.
1 citations
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November 2023 in “Clinical, cosmetic and investigational dermatology” The long-pulse alexandrite laser is good for removing hair and treating skin problems like spots and veins.
1 citations
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September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.
1 citations
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April 2023 in “African Scientific Reports” Natural compounds can lighten skin by reducing melanin.
1 citations
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November 2022 in “Frontiers in medicine” The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.
1 citations
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November 2022 in “Journal of Investigative Dermatology” ALRN-6924 may prevent hair loss caused by chemotherapy.