5 citations
,
January 2021 in “Skin appendage disorders” Smoking is linked to more hair loss and premature graying compared to nonsmokers.
5 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.
4 citations
,
October 2013 in “Springer eBooks” Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
2 citations
,
March 2023 in “Journal of Nepal Medical Association” Many young medical students have early grey hair, especially males, often linked to family history.
2 citations
,
September 2021 in “International Journal of Ayurvedic Medicine” Despite adverse effects, people continue using hair dyes for aesthetic reasons, highlighting the need for safer options.
1 citations
,
January 2015 in “Journal of nutrition & health” Fish oil improves skin health in people with diabetes and high cholesterol.
December 2025 in “MEDFARM Jurnal Farmasi dan Kesehatan” Topical metformin shows promise for treating skin conditions like acne and psoriasis.
January 2025 in “International Journal of Herbal Medicine” Unani medicine effectively reduced premature greying of hair in a 27-year-old man.
January 2020 in “Sumatera Medical Journal” Family history and stress are linked to early hair graying, with family history being the main factor.
Modern hair restoration techniques can effectively treat hair loss and provide natural-looking results.
192 citations
,
June 1992 in “Journal of The American Academy of Dermatology” Hair loss can cause low self-esteem, anxiety, and depression in men.
17 citations
,
July 2014 in “Our Dermatology Online” Older adults have a wide range of skin conditions, with dry skin being very common and many also experiencing skin growths, itching, and infections.
2 citations
,
April 2017 in “Journal of Investigative Dermatology” Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
October 2023 in “Journal of Medicine, University of Santo Tomas (JMUST Online)” Elderly patients frequently suffer from skin conditions, especially inflammatory ones, highlighting the need for better healthcare.
January 2024 in “Dermatology Review” Combining PRP with hydroquinone is more effective for treating melasma than using hydroquinone alone.
759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
260 citations
,
December 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
184 citations
,
November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
155 citations
,
August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution” Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
152 citations
,
December 2007 in “Gender Medicine” Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.
121 citations
,
May 2009 in “Journal of Ethnopharmacology” Eclipta alba extract may help hair grow similarly to Minoxidil.
120 citations
,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
109 citations
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December 1998 in “The Journal of Dermatology” Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
86 citations
,
June 2017 in “Stem cell investigation” Stem cells from hair follicles can safely treat hair loss.
84 citations
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April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
77 citations
,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
71 citations
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February 2006 in “Clinics in Dermatology” Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
67 citations
,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
57 citations
,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.