November 2013 in “Institutional Repositories DataBase (IRDB)” Gamma-ray exposure during hair rest phase harms hair growth and color in mice.
August 2006 in “Experimental dermatology” Human scalp hair follicles can produce and respond to several hormones, affecting hair growth and pigmentation.
22 citations
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January 1985 in “Journal of Human Evolution/Journal of human evolution” Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
1 citations
,
April 2008 in “Pigment Cell & Melanoma Research” Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
222 citations
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January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
152 citations
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December 2003 in “Micron” As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
47 citations
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August 2012 in “Cell Cycle” Stem cells in hair follicles can become neurons and other cells, especially in the upper part, useful for nerve repair.
46 citations
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November 2004 in “Lipids” PPARs help regulate skin health and could be used to treat skin disorders.
21 citations
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January 2019 in “Experimental dermatology” Light therapy using helium-neon lasers can help restore skin color in vitiligo by promoting skin cell growth and movement.
1 citations
,
May 2018 in “International Journal of Molecular Biology Open Access” Hydrogen peroxide is a major risk factor for melanoma in swimmers, more than UV light.
1 citations
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January 2008 in “Springer eBooks” Hair follicle stem cells can turn into many cell types and may help repair nerve damage and have other medical uses.
April 2023 in “Journal of Investigative Dermatology” The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.
November 2022 in “Journal of Investigative Dermatology” Dynlt3 is important for melanosome transport and skin coloration.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Krox20 is important for maintaining stem cells in the skin and affects hair growth and color.
The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.
September 2012 in “British Small Animal Veterinary Association eBooks” The document concludes that pigmentation disorders in animals involve complex interactions between melanocytes and keratinocytes.
October 2021 in “QJM: An International Journal of Medicine” Vitiligo patients have higher hydrogen peroxide levels and lower E-cadherin, affecting skin cell adhesion and pigmentation.
January 2009 in “The Chinese Journal of Dermatovenereology” Higher doses of Tribulus terrestris extract increase MC-1R expression in mouse hair follicles.
1 citations
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December 2020 The skin is the body's largest organ, with layers, cells, and structures that protect and support it.
1 citations
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August 2019 in “Journal of Investigative Dermatology” PRDX5 enzyme may contribute to alopecia areata by affecting oxidative stress and autoimmunity.
23 citations
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June 1992 in “PubMed” RAR-gamma 1 is important for normal skin maintenance and differentiation.
12 citations
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June 2020 in “Sultan Qaboos University medical journal” TRPV4 channel affects skin health and could be a target for treating skin disorders.
10 citations
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April 2022 in “Critical reviews in food science and nutrition” Skin odorant receptors respond to flavors and could be targeted to improve skin health and treat diseases.
2 citations
,
January 2018 Diffuse alopecia areata causes widespread hair thinning due to an autoimmune response.
1 citations
,
October 2025 in “Experimental Dermatology” Mast cells influence skin aging and are potential targets for anti-aging treatments.
1 citations
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January 2022 in “Book Publisher International (a part of SCIENCEDOMAIN International)” Hydrogen peroxide is the main risk factor for melanoma in swimmers, not UV light.
1 citations
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September 2018 in “International journal of research - granthaalayah” Human hair medulla doesn't break down hydrogen peroxide, which may affect hair color formation.
1 citations
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October 2007 in “The Cancer Handbook” Malignant melanoma is the deadliest skin cancer, while BCC is the most common but rarely spreads, and SCC is more aggressive than BCC.
November 2024 in “Journal of Investigative Dermatology” Understanding snoRNA regulation may help slow skin aging.
November 2024 in “Journal of Investigative Dermatology” Blocking the JAK/STAT pathway may help reduce skin sensitivity in Xeroderma pigmentosum.