research Progress in the Development of Stem Cell-Derived Cell-Free Therapies for Skin Aging
Stem cell-derived therapies can help rejuvenate skin by improving wrinkles, elasticity, and pigmentation.
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research Telomere Dynamics and Telomerase in the Biology of Hair Follicles and their Stem Cells as a Model for Aging Research
Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
research Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis
Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
research The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function
The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging
Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
research Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
research Repurposing Metformin for Dermatological Use: Mechanisms, Evidence, and Clinical Perspectives
Metformin shows promise for treating skin conditions, but more research is needed.
research Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging
Reducing IGF-1 can help rejuvenate hair follicles and prevent hair graying and loss.
research Effects of RF Electric Currents on Hair Follicle Growth and Differentiation: A Possible Treatment for Alopecia
RF-based therapies might help treat hair loss.
research GC-TOF/MS-Based Metabolomics for Comparison of Volar and Non-Volar Skin Types
Different types of skin on mice have unique chemical profiles related to how they grow and react to stress.
research Induced Pluripotent Stem Cell Approach to Hair Follicle Regeneration
iPSCs could help develop treatments for hair loss.
research Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices
Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
research Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity
Quiescent adult stem cells are crucial for tissue repair and maintenance.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System
Cannabinoids may help treat various skin conditions.
research Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin
Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
research Macrophages in Skin Wounds: Functions and Therapeutic Potential
Targeting macrophages may improve wound healing.
research Transcriptomic landscape of early hair follicle and epidermal development
Early hair follicle development involves distinct cell populations and Wnt signaling influences cell identity.
research Altered FGF expression profile in human scalp-derived fibroblasts upon WNT activation: implication of their role to provide folliculogenetic microenvironment
WNT activation in scalp fibroblasts boosts hair growth by increasing FGF9.
research Horse hair follicles: A novel dermal stem cell source for equine regenerative medicine
Horse hair follicles could be a new source of stem cells for healing horses.
research Current application of tissue-engineered dermal scaffolds mimicking the extracellular matrix microenvironment in wound healing
Tissue-engineered scaffolds help heal difficult wounds by supporting cell growth and repair.
research Ontogeny of Skin Stem Cells and Molecular Underpinnings
Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
research Early-age-dependent selective decrease of differentiation potential of hair-follicle-associated pluripotent (HAP) stem cells to beating cardiac-muscle cells
Younger mice's hair-follicle stem cells are better at turning into heart cells than older mice's.
research Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease
Zebrafish are useful for studying and developing treatments for human skin diseases.
research Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Epidermal/Dermal Separation Techniques and Analysis of Cell Populations in Human Skin Sheets
Choosing the right method to separate skin layers is key for good skin cell research.
research Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation
Understanding how certain proteins and genetic changes control skin stem cells is key to treating skin diseases.
research Exosome-Based Therapeutics in Dermatology and Beyond: A Narrative Review
Exosome-based treatments may improve skin and hair issues, but more research is needed for safety and effectiveness.
research Mapping Human Skin: One Sequenced Cell at a Time
The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research Neural Potential of a Stem Cell Population in the Hair Follicle
Stem cells in hair follicles can become various cell types, including neurons.