35 citations
,
August 2009 in “Journal of the American Academy of Dermatology” Melanocytes might be targeted by the immune system in people with alopecia areata, but more research is needed.
33 citations
,
December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
26 citations
,
September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
24 citations
,
March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
18 citations
,
August 2021 in “PLoS ONE” Melanocyte progenitor cells are found in human fat tissue and can become mature melanocytes, which may help treat skin issues.
14 citations
,
October 2017 in “Gene Expression Patterns” A new mouse model helps study melanocyte cells using GFP expression.
11 citations
,
April 2013 in “SpringerPlus” Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
10 citations
,
May 2023 in “iScience” Sox9 is crucial for hair follicle stem cells to become melanocytes instead of glial cells.
9 citations
,
June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.
8 citations
,
February 2013 in “Central European Journal of Biology” Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
7 citations
,
October 2011 in “BMC Cancer” Overexpression of HDGF in melanocytes does not cause cancer.
5 citations
,
September 2018 in “Journal of Investigative Dermatology” Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.
4 citations
,
May 2023 in “Pigment Cell & Melanoma Research” BMI1 is essential for preventing hair greying and maintaining hair color.
4 citations
,
February 2023 in “International Journal of Stem Cells” The FTO gene hinders stem cells in hair follicles from becoming pigment cells.
4 citations
,
January 2019 in “Micron” Fetal hair follicles have melanocytes with melanosomes at different stages, which are broken down into pigment particles in keratinocytes.
4 citations
,
May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
3 citations
,
September 2023 in “Stem Cell Research & Therapy” Stem cells can be used to create long-lasting skin cells for treating pigment disorders.
3 citations
,
October 2020 in “Journal of Investigative Dermatology” Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.
1 citations
,
August 2022 in “Pigment Cell & Melanoma Research” New mouse models help study melanocytic cells for melanoma research.
1 citations
,
January 2021 in “Processes” Researchers successfully grew horse skin cells that produce pigment from hair follicle samples.
1 citations
,
December 2018 in “IOP conference series. Materials science and engineering” CD34+ hair follicle stem cells can become melanin-producing cells for treating skin conditions.
1 citations
,
January 2014 in “Elsevier eBooks” Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
September 2023 in “Journal of the American Academy of Dermatology” BAP1 mutations are rare in pediatric melanocytic tumors and may develop later in life.
April 2026 in “npj Regenerative Medicine” Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
November 2025 in “EXPERIMENTAL ANIMALS” Stingless bee propolis may help regenerate hair follicles and improve pigment function in chemotherapy-induced hair loss.
February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair follicles protect melanocytes from sun damage, helping them replenish skin.
January 2025 in “American Journal of Stem Cells” Melanocyte stem cells hold promise for skin regeneration and treating pigmentation issues.
August 2024 in “Animal Bioscience” Exosomal miR-222-3p reduces melanin production in rabbits by targeting the SOX10 gene.
April 2024 in “Pigment cell & melanoma research” Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
April 2024 in “Journal of translational medicine” Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.