17 citations
,
July 2013 in “Amino Acids” Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
14 citations
,
December 1998 in “British Journal of Cancer” Truncated hHb1 keratin may play a role in breast cancer cell transformation.
3 citations
,
August 2022 in “International Journal of Molecular Sciences” TSC2-/meth cells can cause skin lesions, hair growth, and lung issues, and may be treated with chromatin remodeling agents.
February 2026 in “bonndoc (University of Bonn)” New gene variants were found for rare skin and hair disorders, improving understanding and treatment.
7 citations
,
January 2008 in “Indian Journal of Dermatology” Pigmentary mosaicism causes skin color changes and can affect multiple body systems, but has no cure.
14 citations
,
October 2021 in “Dermatology and Therapy” UV exposure accelerates skin aging by altering elastin, leading to wrinkles.
185 citations
,
February 2018 in “Journal of Investigative Dermatology” Melatonin may benefit skin health and could be a promising treatment in dermatology.
April 2016 in “Journal of Investigative Dermatology” Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.
March 2014 in “Chinese Journal of Dermatology” Hair loss in androgenic alopecia patients is linked to changes in certain genes that control cell growth and death.
48 citations
,
June 2000 in “Japanese Journal of Cancer Research” Dimethylarsinic acid speeds up skin tumor growth in certain mice.
1 citations
,
October 2022 in “Research Square (Research Square)” Melatonin helps improve Cashmere goat hair quality by promoting hair follicle growth through a specific cell signaling pathway.
January 2019 in “Advances in stem cells and their niches” Krox20 is important for cell differentiation in the brain and hair follicles.
January 2010 in “Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine” A unique gene mutation was found in a family with monilethrix.
5 citations
,
May 2023 in “Frontiers in Cell and Developmental Biology” Integrin α6 helps identify different neural crest cell types in the skin.
January 2008 in “HAL (Le Centre pour la Communication Scientifique Directe)” The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.
17 citations
,
October 2021 in “Cellular & Molecular Biology Letters” New biomarkers and potential treatments for skin diseases were identified.
September 2022 in “Scientific Reports” Scalp melanoma is more common and easier to diagnose early in people with androgenetic alopecia due to sun damage.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
28 citations
,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
6 citations
,
February 2013 in “Journal of Visualized Experiments” The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
1 citations
,
December 2022 in “BMC Genomics” The Msx2 gene affects feather development in Hungarian white geese and a specific gene variation could indicate feather quality.
April 2018 in “Journal of Investigative Dermatology” Id2 gene helps keep hair follicle stem cells inactive.
20 citations
,
September 2021 in “Nature communications” Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
January 2014 in “Pathology” Early subungual melanoma might be treated with less aggressive surgery because it invades the skin under the nail more slowly.
7 citations
,
November 2016 in “Oncotarget” UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
3 citations
,
January 2014 Collagen XVIII and Bmx tyrosine kinase are important for hair growth and skin cancer development.
19 citations
,
March 2018 in “Journal of Investigative Dermatology” The gene Msx2 is crucial for hair follicle regeneration during wound healing.
3 citations
,
September 2022 in “Frontiers in veterinary science” Melatonin affects cashmere growth in goats by influencing stem cell and certain signaling pathways.
297 citations
,
January 2002 in “Development” Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.
45 citations
,
March 1997 in “Journal of Investigative Dermatology”