4 citations
,
December 2023 in “Frontiers in Pharmacology” Topical metformin effectively treats melasma with minimal side effects.
1 citations
,
June 2025 in “Journal of Cellular and Molecular Medicine” Plant-derived compounds may help reverse grey hair by boosting melanin production.
December 2024 in “Health Science Reports” Topical metformin shows promise for dental and skin treatments, including periodontitis, hair regrowth, wound healing, and acne.
December 2023 in “Journal of ethnopharmacology” Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
37 citations
,
July 2002 in “Archives of Pathology & Laboratory Medicine” Tyrosinase and gp100 proteins can help diagnose and treat melanoma.
23 citations
,
May 2023 in “Cell Proliferation” TGF-β and FGF pathways are crucial for skin development and regeneration.
August 2025 in “World Academy of Sciences Journal” Topical metformin shows promise for skin treatments but needs more testing for safety and effectiveness.
80 citations
,
April 2006 in “Clinical Interventions in Aging” Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
20 citations
,
February 2023 in “Biology” Innovative cosmetics could safely change hair color by targeting biological hair pigmentation processes.
13 citations
,
September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
10 citations
,
September 2021 in “International Journal of Nanomedicine” Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
8 citations
,
July 2020 in “Clinical, cosmetic and investigational dermatology” Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
7 citations
,
December 2021 in “Archives of Dermatological Research” Adiponectin reduces hair pigmentation and affects hair growth signals.
4 citations
,
May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
3 citations
,
December 2024 in “International Journal of Dermatology” Premature hair graying is caused by genetics, stress, and lifestyle, and affects mental health.
3 citations
,
September 2023 in “Stem Cell Research & Therapy” 3 citations
,
November 2022 in “Frontiers in Oncology” Melanin may help melanoma cells grow by aiding their metabolism.
2 citations
,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
March 2026 in “Preprints.org” The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
January 2026 in “Cosmetics” The fermented solution from Platycladus orientalis leaves may boost hair growth and reduce inflammation.
January 2026 in “Molecules” Dihydroartemisinin could be a versatile cosmetic ingredient but needs more research and development.
November 2025 in “The Journal of Dermatology” Chemical leukoderma is temporary, while chemical-induced vitiligo can be persistent and harder to treat.
January 2019 in “International Journal of Plant Animal and Environmental Sciences” The extract from marine green alga Chlamydomonas sp. W80 has antioxidant, anti-inflammatory, anti-aging, hair growth, immune-boosting, and skin lightening effects.
January 2018 in “대한본초학회지(본초분과학회지)” The herbal extract SHJ promotes hair growth and increases melanin production.
70 citations
,
December 2004 in “Proceedings of the National Academy of Sciences” BMP signaling affects hair color by interacting with the MC-1R pathway.
56 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
26 citations
,
December 2022 in “Molecules” Nanotechnology can improve treatments for skin discoloration.
17 citations
,
April 2023 in “ACS Biomaterials Science & Engineering” Silk fibroin microneedles can effectively treat vitiligo by promoting skin pigmentation.
9 citations
,
January 2015 in “Annals of dermatology/Annals of Dermatology” Alopecia areata in elderly people is usually mild and responds well to treatment.
44 citations
,
January 2015 in “Development” Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.