research Hair(y) Matters in Melanoma Biology
The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
Search
for
Sort by
Research
30-60 / 1000+ results 
research Preliminary evaluation of reflectance confocal microscopy features of scalp melanoma
Reflectance confocal microscopy is useful for diagnosing scalp melanomas, which have features similar to those on the trunk.
research Dormant tumor cells in ret transgenic mouse melanoma model and their interaction with memory T cells
Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.
research Cutaneous malignant melanoma incidences analyzed worldwide by skin type over advancing age of males and females: Evidence estrogen and androgenic hair are risk factors
Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research ‘Malignant melanoma microecosystem’: Immunohistopathological insights into the stromal cell phenotype
Stromal cells in melanoma promote tumor growth and spread.
research Characteristics of non‐melanoma skin cancers of the cutaneous perioral and vermilion lip treated by Mohs micrographic surgery
Mohs micrographic surgery is effective for early-stage non-melanoma skin cancers on the lips, with basal cell carcinoma more common on the upper cutaneous lip and squamous cell carcinoma more common on the lower vermilion lip.
research Clinical Case Notes. Malignant melanoma in eviscerated eyeball
Finasteride, often used for hair loss, can potentially cause cataracts.
research Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways
Securinine and ajmaline may effectively treat liver cancer, with securinine being less toxic to normal cells.
research Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape
Small molecules KY19382 and KY19334 may help treat skin cancer by reducing CDK1 levels and blocking harmful cell signals.
research METTL1-mediated m7G tRNA modification drives papillary thyroid cancer progression and metastasis by regulating the codon-specific translation of TNF-α
Targeting METTL1 may help slow papillary thyroid cancer growth and spread.
research Skin health of community-living older people: a scoping review
Older people at home often have skin issues, but there's little evidence on how to prevent or treat them effectively.
research A symphony of signals: the intricate role of lncRNAs in dermatological disorders
lncRNAs are important for understanding and treating skin diseases.
research Uncovering the complex relationship between balding, testosterone and skin cancers in men
Men with baldness are more prone to skin cancers on the scalp due to sun exposure, not testosterone.
research Estrogens and aging skin
Estrogen therapy can reduce skin aging but has cancer risks.
research Obesity and the skin
Obesity is linked to various skin problems and may increase the risk of skin cancer.
research Molecular Regulation of Melanocyte Senescence
The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
research The population dynamics of cancer: a Darwinian perspective
Cancer development is like natural selection, involving mutated cells and environmental factors.
research Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Application of multiphoton microscopy in dermatological studies: A mini-review
Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
research Defining Hair Follicles in the Age of Stem Cell Bioengineering
The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
research Skin disorders in Parkinson’s disease: potential biomarkers and risk factors
Certain skin conditions may indicate or increase the risk of Parkinson's disease.
research Potential Therapeutic Applications of Bee Venom on Skin Disease and Its Mechanisms: A Literature Review
Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.
research Parkinson's disease and skin
Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.
research Genome-wide association study of skin complex diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research INTERFERONS IN DERMATOLOGY
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Exosomes as a novel pathway for regulating development and diseases of the skin (Review)
Exosomes are important for skin health and could help diagnose and treat skin diseases.
research Dermoscopy: not just for dermatologists
Dermoscopy is useful for many health professionals, not just dermatologists, in improving skin condition diagnoses and reducing unnecessary biopsies.
research Use of H-1 Antihistamine in Dermatology: More than Itch and Urticaria Control: A Systematic Review
H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.
research Why Do Promising Therapies Stall in Development and How Can We Move Them Forward?
Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.