81 citations
,
October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.
January 2010 in “Chinese Journal of Aesthetic Medicine” Melasma skin has more melanin and signs of aging, with strong CK10 expression linked to cell differentiation and aging.
September 2016 in “Journal of Dermatological Science” Polarizing light microscopy can easily and reliably diagnose congenital keratinizing disorders like Netherton syndrome.
July 2025 in “Journal of Investigative Dermatology” Miniaturized hair follicles in androgenetic alopecia show abnormal mitochondrial activity and damage.
1 citations
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October 2007 in “The Cancer Handbook” Malignant melanoma is the deadliest skin cancer, while BCC is the most common but rarely spreads, and SCC is more aggressive than BCC.
2 citations
,
January 2014 in “Photochemical & photobiological sciences” Grasp protein helps maintain skin health after UVB exposure.
11 citations
,
February 2018 in “Archives of Pharmacal Research” Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
11 citations
,
August 1987 in “Archives of Dermatology” Langerhans' cells are not involved in hair depigmentation in these mice.
92 citations
,
January 1999 in “Physics in Medicine and Biology” Skin can be cooled quickly and safely during laser treatments to protect it without affecting deeper layers.
75 citations
,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
55 citations
,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
45 citations
,
April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
33 citations
,
January 2021 in “Aesthetic Surgery Journal” Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.
30 citations
,
June 2006 in “British journal of dermatology/British journal of dermatology, Supplement” Oral zinc sulphate reduces dark hair color in mice.
20 citations
,
April 1999 in “British journal of plastic surgery” Ruby laser hair removal significantly reduces hair density.
15 citations
,
July 1999 in “Dermatologic Clinics” The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
10 citations
,
November 2016 in “International Journal of Cosmetic Science” A tough membrane between the outer and inner layers of human hair protects it from damage.
10 citations
,
May 2016 in “Journal of Dermatological Science” PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
4 citations
,
November 2016 in “Dermatologic Therapy” Topical tretinoin may increase beard hair density.
2 citations
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May 2018 in “Australasian Journal of Dermatology” Some patients' hair grew back black and white after chemotherapy.
2 citations
,
January 2018 in “International Journal of Advanced Community Medicine” The cream effectively reduces hyperpigmentation and signs of aging without causing skin irritation.
2 citations
,
January 2017 in “Journal of Pigmentary Disorders” Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.
2 citations
,
January 2002 Melanin and melanocytes contribute to the brown pigmentation in stasis dermatitis.
February 2026 in “Chinese Medicine” Natural products might help treat hair greying.
May 2021 in “Open Access Macedonian Journal of Medical Sciences” People with premature hair graying have an imbalance between harmful and protective molecules in their body, hinting that antioxidants might help.
January 1999 in “Journal of Investigative Dermatology” July 2024 in “Journal of Investigative Dermatology” Topical melatonin may reduce skin aging by inhibiting certain cellular pathways.
133 citations
,
May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
August 2021 in “Annals of pathology and laboratory medicine” Most skin tumors in the study were benign, with squamous cell carcinoma being the most common malignant type.