research The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted
The risk of skin tumors becoming malignant depends on the specific skin cell type affected.
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780-810 / 1000+ resultsresearch EFFECTS OF α-MELANOCYTE-STIMULATING HORMONE AND [8-ARGININE]-VASOTOCIN UPON MELANOGENESIS IN HAIR FOLLICLE MELANOCYTES IN VITRO
α-MSH increases melanin production in moulting hair follicles, while AVT inhibits it.
research Dual aspects of B cells in tumor immunity; B cells are capable of positive and negative regulation for tumor immunity against B16 melanoma
B cells can both help and hinder the body's defense against melanoma.
research Percutaneous penetration of hair dyes
Hair dyes penetrate the scalp very minimally, less than 1%.
research SCA-1+ Cells with an Adipocyte Phenotype in Neonatal Mouse Skin
Sca-1+ cells in newborn mouse skin may become fat cells.
research Nevus psiloliparus: Newly described histopathological features from transverse sections
Nevus psiloliparus lacks mature hair follicles but keeps other skin structures intact.
research Metastatic Melanoma of the Tongue: A Rare Case
An 86-year-old man had a rare tongue melanoma but refused treatment, showing the need for early cancer detection and treatment.
research Differential Expression of MITF, WNT3A, SLC7A11, and EDN3 in the Shoulder ‘Bider Marking’ of Dun Mongolian Horses
MITF and WNT3A are key in Dun Mongolian horse pigmentation.
research Multiscale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
research The color of human hair
Human hair color is determined by melanin types and genetic factors.
research Subungual melanocytic lesions
Early subungual melanoma might be treated with less aggressive surgery because it invades the skin under the nail more slowly.
research Selective follicular targeting by modification of the particle sizes
Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.
research Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis
Skin cells control immune cell placement, helping the skin respond better to challenges.
research Vitiligo
Vitiligo causes white skin patches and is linked to autoimmune issues.
research The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis
The PML protein helps prevent skin cancer in mice.
research 0750 Proteomics and transcriptomics profiling define molecular subtypes of advanced cutaneous T cell lymphoma and prognostic biomarkers
Three molecular subtypes of advanced skin T-cell lymphoma were identified, with potential biomarkers for predicting treatment response and disease progression.
research 645 MIG6 is MEK-regulated and affects EGF-induced migration in mutant NRAS melanoma
Decreasing MIG6 can increase the movement and invasiveness of MEK-inhibited mutant NRAS melanoma, particularly when stimulated by EGF.
research Prognostic Significance of a Positive Nonsentinel Lymph Node in Cutaneous Melanoma
Finding a positive nonsentinel lymph node in melanoma patients indicates a worse prognosis.
research A Short Report on Melanocyte/Melanoma Culture, Senescence, and Reproducibility
Clear documentation and shared best practices are essential for improving research consistency in pigment cells.
research Disorders of pigmentation in infants and children
Vitiligo causes white skin patches, often starts before age 20, and is linked to other health issues.
research Immunohistochemical Pattern of CD34 Distribution in Different Types of Basal Cell Carcinoma and in Peritumoral Skin
CD34 is absent in most basal cell carcinoma cells but present in surrounding skin.
research Diagnosis and Management of Melanoma of the Scalp: A Review of the Literature
Scalp melanoma, a deadly skin cancer, is often found late due to its hard-to-see location, especially in older men. Early detection, possible treatments, and the role of hairdressers in spotting it early are discussed. More research is needed to improve detection and treatment.
research Lymphoproliferative Disorders: Hot Topics in Dermatology 2019
The document updated knowledge on skin disorders, focusing on unusual moles in older adults, the progression from moles to melanoma, and evolving hair loss treatments.
research The antimycotic agent clotrimazole inhibits melanogenesis by accelerating ERK and PI3K-/Akt-mediated tyrosinase degradation
Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.
research Skin precancer.
Sun exposure and genetics increase skin cancer risk from precancerous lesions.
research Dermoscopy findings of alopecia areata in an African-American patient
Skin color may change how alopecia areata looks under a dermoscope.
research Synergy of understanding dermatologic disease and epidermal biology
Advancements in skin and hair biology improve dermatology care and cosmetic treatments.
research The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: the Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma
Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.
research Repigmentation through Melanocyte Regeneration in Vitiligo
UV light can help stimulate the growth of new pigment cells from hair follicles in people with vitiligo.
research MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters
MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.