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Alpha-MSH affects mitochondrial function, and MC1R mutations may increase skin aging.

α-MSH may help treat skin inflammation and fibrosis.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

Lentiginous melanoma is most common on the face, especially the nose, cheek, and pre-auricular areas, with men more likely to have it on the scalp, ears, upper back, and trapezius, and women on the cheek and anterior arm. Sun damage is a key factor in its formation.

miR-5110 affects alpaca pigmentation by altering specific gene expressions.

Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.

A new molecule was found to be a safe and effective skin lightener and anti-aging product.

Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.

The review suggests that there are various treatments to help restore skin color after severe burns.

Vitamin B12 deficiency can cause reversible skin darkening.

Pigmentary mosaicism causes skin color changes and can affect multiple body systems, but has no cure.

The treatment improved hair color in most vitiligo patients without major side effects.

As Japanese males age, their hair darkens due to increased melanin, with males generally having darker hair than females.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Pigmented rings with central clearing help diagnose melasma more accurately.

Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.

Synthetic hormone treatment reduces melanin and hair growth in rats.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

Rhododendrol in skin-whitening products can cause skin depigmentation and immune reactions.

TRH in hair follicles can influence hair color by increasing melanin.

Oral zinc sulphate reduces dark hair color in mice.

Hair color is not a risk factor for developing alopecia areata.

Platelet-rich plasma (PRP) can significantly improve melasma, a skin pigmentation disorder, but may not add benefits when used with certain other treatments.

Hair and nail disorders can cause changes in scalp pigmentation, especially with sun exposure and alopecia.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Melatonin may protect skin from radiation, but its effects on aging and hair growth are unclear.

Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.

A specific group of early-stage melanocytes is reduced in vitiligo-affected skin, which may explain treatment resistance.

Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.

Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.