August 2023 in “Portuguese journal of dermatology and venereology” Cyclosporine can reverse hair graying.
16 citations
,
October 2009 in “Xenobiotica” The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.
73 citations
,
December 2015 in “Nature Genetics” Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.
55 citations
,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
6 citations
,
August 2019 in “PLOS ONE” Gambogic Amide helps maintain hair color and promotes hair growth.
4 citations
,
November 2022 in “British Journal of Cancer” Men with melanoma have a higher risk of later being diagnosed with prostate cancer.
April 2016 in “Journal of Investigative Dermatology” Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.
February 2025 in “International Journal of Molecular Sciences” Altered lipid pathways in diabetic women may cause premature greying.
260 citations
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June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
1 citations
,
May 2017 in “Journal of Stem Cell Research & Therapeutics” Pluripotent stem cells show promise for treating skin color loss disorders like vitiligo.
64 citations
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June 2009 in “Photomedicine and Laser Surgery” Excimer light effectively treats various skin diseases, including psoriasis, vitiligo, and mycosis fungoides.
8 citations
,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
2 citations
,
March 1997 in “Veterinary Dermatology” The Doberman had multiple skin tumors, but it's unclear if color dilution increased the risk.
11 citations
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January 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.
December 2025 in “Dermatology Reports” Topical ruxolitinib quickly improves non-segmental vitiligo.
46 citations
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April 2005 in “Melanoma Research” Skin diseases look different on pigmented and nonpigmented skin.
March 2026 in “International Journal of Science and Research (IJSR)” Melatonin protects skin and supports hair growth.
June 2017 in “Journal of The American Academy of Dermatology” The new treatment was safe and may effectively treat male pattern hair loss.
20 citations
,
February 2024 in “Anais Brasileiros de Dermatologia” Black skin needs more focused dermatology research for better diagnosis and treatment.
August 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.
4 citations
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March 2018 in “PloS one” Men with less sun-sensitive skin have lower PSA levels, while men with more sun-sensitive skin have higher PSA levels.
1 citations
,
November 2023 in “BMC chemistry” Tadalafil and Finasteride may help treat aggressive melanoma.
40 citations
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January 2013 in “Clinical Cosmetic and Investigational Dermatology” Desonide is more effective than niacinamide for reducing underarm darkening.
April 2026 in “Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy”
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” A 73-year-old woman with Hypopigmented Mycosis Fungoides, a rare skin lymphoma, experienced disease progression despite treatment, emphasizing the need for ongoing monitoring.
Melatonin affects cell growth differently based on its concentration.
Tailored nonsurgical cosmetic procedures are crucial for safely treating diverse skin types, especially skin of color.
11 citations
,
November 1991 in “Journal of Neuropathology & Experimental Neurology” Brindled mice show abnormal catecholamine neuron development due to copper deficiency.