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Merck will refund the cost of the drug finasteride if it doesn't improve symptoms within six months or if the patient needs surgery within two years.

Mercaptans make hair more prone to damage, with reduced hair being more affected than permed hair.

New pyrazole derivatives may help treat hair loss, but more testing is needed.

The book helps veterinarians understand and treat hair loss in animals.

Frontal fibrosing alopecia and vitiligo might be linked by similar immune issues.

Finasteride is stable except in high pH, and lactose and magnesium stearate should be replaced in formulations.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

The book "Practical Contact Dermatitis" is useful for dermatologists but could be more user-friendly.

MARCKSL1 is important for wound healing and could be a target to reduce scarring.

Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

Cysteine formation on hair indicates damage, best detected at pH 4.5.

Human nails contain both skin and hair keratins, each needing different extraction methods.

Certain treatments can increase protein binding to natural hair but are less effective on permed hair.

Guinea pig fat stem cells can become hair cell-like cells in a lab.

Finasteride, originally for prostate issues, also treats hair loss, similar to effects from certain plants.

Finasteride can help regrow hair in male pattern baldness.

Fludalanine failed as an effective oral antibiotic despite efforts.

Finasteride must now warn about lasting sexual side effects.

1% minoxidil didn't improve hair growth for severe alopecia areata.

Untreated androgenetic alopecia leads to progressive hair loss in men.

The document updates on EU legal changes, including pharmaceutical patents, class actions in Italy, and various drug-related rulings.

The UK Court of Appeal ruled that new dosing regimens for drugs can be patented, aligning with the European Patent Office's approach.

The UK Intellectual Property Office allows granting of supplementary protection certificates with negative terms.

MK-386 reduces sebum DHT levels.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Bayesian networks are tools for modeling variables' probabilistic relationships, which can efficiently represent complex probabilities and help in making inferences.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

Finasteride discontinuation increases sperm count in men.

UK courts and the European Patent Office are now more open to granting patents for new dosage regimes.