65 citations
,
December 2000 in “PubMed” The biology of skin and hair is complex and not fully understood.
15 citations
,
September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
November 2014 in “Journal of Cell Biology” Valentina Greco's research shows that the environment around hair follicle stem cells is more crucial for regeneration than the stem cells themselves.
March 2026 in “Journal of Drugs in Dermatology” Exosome-based therapies may improve skin conditions but need more research for safety and effectiveness.
13 citations
,
January 2021 in “Regenerative Medicine” Platelet lysate could be a valuable treatment for many diseases in regenerative medicine.
July 2025 in “ACS Applied Materials & Interfaces” Ultrasound-activated gel with stem cell vesicles improves skin healing and regeneration.
July 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Ultrasound and GelMA hydrogel with stem cell vesicles improve skin healing and regeneration.
June 2025 in “Journal of Cosmetic Dermatology” Excessive scalp massage after using minoxidil can cause hair damage, but reducing massage and using MSC exosomes can help.
December 2024 in “Drug Discoveries & Therapeutics” Baricitinib-loaded EVs help hair regrowth in alopecia areata by reducing inflammation and promoting hair follicle regeneration.
MSC-CM cream speeds up burn wound healing better than the control treatment.
February 2023 in “Journal of Aesthetic Nursing” Various hair restoration methods can effectively promote hair growth.
20 citations
,
June 2020 in “Stem Cell Research & Therapy” Using stem cells from fat tissue can significantly improve wound healing in dogs.
218 citations
,
April 2008 in “Genes & Development” Skin stem cells help repair damage and maintain healthy skin.
36 citations
,
July 2014 in “Experimental Dermatology” Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
24 citations
,
November 2019 in “Experimental Dermatology” PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
February 2025 in “Stem Cell Research & Therapy” Hair follicle regeneration is advancing but still faces challenges in stability and clinical use.
August 2023 in “Molecules and Cells” Hair can regrow after significant damage through a process similar to how it forms before birth, involving stem cells and various cell types and signals. This could be a new way to prevent scarring and promote hair growth.
January 2020 in “Open University of Cape Town (University of Cape Town)” Efficient culture methods are needed to keep human keratinocytes undifferentiated for hair follicle induction.
December 2013 in “Research Portal (King's College London)” Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
Recent discoveries have improved our understanding of hair loss, but challenges in treatment and knowledge among specialists still exist.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
165 citations
,
October 2013 in “Nature Communications” Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.
3 citations
,
January 2021 in “Oxidative Medicine and Cellular Longevity” Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
September 2025 in “PubMed” Regenerative hair transplant improves hair growth and quality using stem cells.
July 2022 in “Plastic surgery and modern techniques” Using stem cell-enriched fat injections before hair transplant surgery can result in less hair loss and thicker hair.
November 2018 in “Journal of Investigative Dermatology” Lichen Planopilaris causes irreversible hair loss due to immune attacks on hair stem cells, but modulating PPAR-γ might help treat it.
December 2010 in “Journal of Oriental Medicine” Black bean, wheat, and rice bran extracts can improve hair growth and quality.
November 2014 in “Surgical research updates” Platelet Rich Plasma (PRP) may improve hair transplant success by increasing blood vessel and hair follicle growth.
16 citations
,
September 2022 in “Cold Spring Harbor Perspectives in Biology” Wound healing can potentially regrow hair and aid in hair loss treatments.
10 citations
,
September 2022 in “Cellular and Molecular Life Sciences” SOX9 is essential for the development of various organs and hair follicles.