November 2025 in “Journal of Investigative Dermatology” Mesenchymal stiffness affects sweat gland cell development.
6 citations
,
June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
August 2019 in “Journal of Investigative Dermatology” Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
2 citations
,
February 2024 in “Nature cell biology” Mechanical forces are crucial for shaping cells and forming tissues during development.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.
83 citations
,
January 2023 in “Development” Hox genes are crucial for development and tissue maintenance, affecting structures and functions throughout life.
11 citations
,
January 2010 in “Dermatology Research and Practice” Desmosomes are crucial for human skin development, increasing in density as the skin matures.
25 citations
,
July 2015 in “EMBO Reports” Tmem50b and 2610305D13Rik genes play key roles in early mouse embryo development.
84 citations
,
October 2014 in “PLoS Genetics” Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
January 2018 in “VCU Scholars Compass (Virginia Commonwealth University)” Desmosomes are crucial for skin and heart development, and JNK may help regulate them.
29 citations
,
July 2014 in “PloS one” Meis1 is crucial for skin health and tumor development.
April 2026 in “Development” Hemidesmosomes and Notch signaling help skin cells mature by moving them to the outer layer.
43 citations
,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
January 2023 in “Theranostics” Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
2 citations
,
August 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Hoxd gene regulation in mammals and birds is robust despite differences in DNA sequences, due to 3D chromatin structures.
61 citations
,
April 1980 in “Journal of the American Academy of Dermatology” A new syndrome may link skin, growth, mental, and hair issues.
May 2024 in “Cell proliferation” Melatonin helps hair grow by activating a specific signaling pathway.
65 citations
,
August 2013 in “Acta Biomaterialia” The new matrix improves skin regeneration and graft performance.
32 citations
,
February 2019 in “eLife” BMP signaling is essential for the development of touch domes.
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
12 citations
,
August 2007 in “Human Molecular Genetics” Lymphotoxin-β is crucial for proper skin development in embryos.
318 citations
,
October 1998 in “The Journal of Cell Biology” Keratin 17 is important for skin development and may help define skin cell types.
19 citations
,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Ezh2 controls skin development by balancing signals for dermal and epidermal growth.
2 citations
,
April 2019 in “Experimental Dermatology” The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
Retinoic acid can change skin development, like turning scales into feathers or forming glands.
17 citations
,
January 2013 in “Journal of Cutaneous Pathology” The onychodermis helps anchor the nail bed and may aid in nail formation.
42 citations
,
February 2000 in “Journal of Investigative Dermatology” Type VII collagen absence helps skin development by allowing tissue remodeling.
51 citations
,
May 2021 in “Nature Communications” High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
May 2018 in “Cell stem cell” Myoepithelial cells can repair airways after severe injury.