233 citations
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November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
65 citations
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August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
41 citations
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July 2001 in “PubMed” Estrogens can reduce DHT production in hair follicles, but are less effective than finasteride and progesterone.
4 citations
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April 2001 in “Experimental Dermatology” Using single dermal papillae is unreliable for analyzing androgen metabolism in hair follicles.
3 citations
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March 2022 in “Research journal of pharmacy and technology” Parsley contains compounds that might be good for treating hair loss.
November 2022 in “Journal of the Endocrine Society” Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.
7 citations
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August 2023 in “Life” Extracellular vesicles could help tailor drug treatments, but more research is needed.
January 2026 in “MEDS Clinical Medicine” Biophysical and metabolic factors in skin wounds are crucial for stem cell behavior and skin healing.
October 2025 in “Biomolecules” Intermittent fasting improves metabolism and reduces obesity by affecting specific molecules in fat tissue.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.
22 citations
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May 1986 in “Clinics in endocrinology and metabolism” Certain finger length ratios and body hair patterns may predict side effects from birth control pills in women.
14 citations
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July 2016 in “Journal of Endocrinology” The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.
11 citations
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October 2002 in “Pharmacology Biochemistry and Behavior” Formalin-induced pain increases testosterone breakdown in the rat brain and spinal cord.
January 2026 in “Industrial Crops and Products” Ginsenoside Rf from Panax ginseng promotes hair growth and could be a natural alternative for treating hair loss.
January 1978 in “Enlighten: Theses (The University of Glasgow)” Inhibiting testosterone 5alpha-reductase may help treat benign prostatic hyperplasia.
82 citations
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October 2019 in “Frontiers in Immunology” Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
40 citations
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December 2016 in “Journal of Ovarian Research” Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
31 citations
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January 1995 in “The American journal of medicine” Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
10 citations
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August 1990 in “Journal of Steroid Biochemistry” High doses of cyclosporine A increase testosterone conversion, possibly boosting hair growth.
4 citations
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September 2006 in “European Journal of Clinical Pharmacology” Finasteride doesn't affect omeprazole metabolism in Japanese people.
1 citations
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January 2021 in “European Journal of Inflammation” Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
September 2024 in “Quality in Sport” Diet and exercise are key to managing PCOS symptoms.
34 citations
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February 1999 in “Journal of Dermatological Science” Minoxidil boosts enzymes that help hair growth.
Antiandrogens and finasteride may help treat excess hair and hair loss in women.
5 citations
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September 2023 in “Molecules” These methods help understand cell structures and reactions.
5 citations
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January 2019 in “cIRcle (University of British Columbia)” A high fiber, low glycemic diet, exercise, and stress management can help reduce PCOS symptoms.
January 2022 in “Social Science Research Network” Pyruvate Kinase M2 helps hair grow by linking energy production and a key hair growth pathway.
25 citations
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September 2005 in “International Journal of Developmental Neuroscience” Morphine increases testosterone breakdown in the rat brain and spinal cord.
January 1999 in “Proceedings of the British Society of Animal Science” Biotin deficiency may harm hair follicle health and growth in Angora goats.
1 citations
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May 2022 in “Frontiers in Pharmacology” Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.