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The study found that in Eclipta prostrata roots, coumestans come from acetate and shikimate pathways, and phenylpropanoid is made only through the shikimate pathway.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Drugs can be incorporated into hair based on their chemical properties and hair pigmentation.

Doctors need to recognize and treat metabolic disorders in children early to prevent serious health issues.

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

Ginsenoside compound K shows promise for treating metabolic diseases like obesity and diabetes, but more research is needed on its safety and effectiveness.

Psychotropic drugs can interact with natural products, affecting their effectiveness and safety.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Plant bioactive compounds are important for health and can help prevent various diseases.

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.

Beard hair follicles convert testosterone to 5α-dihydrotestosterone most intensively.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Compounds from Pterocarpus indicus may help treat benign prostatic hyperplasia by stopping cell growth.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.

The study created a new method to test drugs that affect hormone processing in skin.

Metabolite 7 is a strong inhibitor for Alzheimer's disease management.

Canine hair follicle cells convert progesterone into various metabolites, mainly cortisol.

Finasteride is extensively metabolized in the body, affecting its effectiveness and safety.

The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.

Finasteride's metabolites were identified, helping understand how the drug is processed in the body.

Microextraction techniques improve hormone testing while being environmentally friendly.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.