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TTD hair is brittle due to fewer sulfur amino acids and unstable disulfide bonds.

Vitamin B12 deficiency can cause darkening of all nails.

Liver damage in PCOS is linked to iron overload and cell death due to the miR-761-hepcidin/GPX4 pathway.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Targeting mitophagy may help treat alopecia areata by reducing inflammasome activation.

A TNFAIP3 gene mutation can cause unusual and varied symptoms of lupus and Sjogren's syndrome.

Higher levels of chromium, selenium, and copper in hair are linked to increased insulin resistance in visceral-obese adults.

New mutations in MBTPS2 reduce its function and cause IFAP syndrome with unusual symptoms.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Calprotectin starves Pseudomonas aeruginosa of essential metals, affecting its growth and resistance.

Five different TPO gene mutations were found in PCOS patients with thyroid hormone issues.

FTase and GGTase-I are essential for skin keratinocyte health.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.

Researchers found two new genetic variants linked to Alzheimer's disease.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Mitochondrial reactive oxygen species are essential for skin and hair development.

BDNF, TSH, fT4, anti-TPO, and 25-OH Vitamin D levels predict depression risk in patients with autoimmune thyroiditis and hypothyroidism.

Tay syndrome is a unique genetic disorder causing skin, hair, and developmental issues.

A rare case of isolated trichothiodystrophy was identified, marked by brittle hair with low sulfur content.

SOD1 and KL are promising targets for new hair loss treatments.

Certain genes in European Merino sheep help them adapt to different climates.

Selenium in hair and nails is higher with L-selenomethionine and low methionine.

Introducing the rat OTC gene normalized hair growth in SPF-ASH mice.

MC1R gene variations affect skin, hair color, UV sensitivity, and melanoma risk.

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Thallium poisoning can be identified through radiological signs and treated effectively with B.A.L.