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Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.

Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.

Dutasteride mesotherapy helps treat male hair loss but may harm sperm and sexual function.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

High testosterone levels can harm fertility by disrupting the LIF signaling pathway in the uterus.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.

A rare ovarian tumor caused high male hormone levels, but surgery fixed it.

Mouse hair cells respond to male hormones by growing less, and this can be stopped by certain blockers.

Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Testosterone therapy had limited benefits for a man with depression and suspected low testosterone, highlighting the need for careful diagnosis and treatment planning.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

Researchers found four natural compounds that can change DHT levels in prostate cancer cells.

11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.

Confirm testosterone levels with advanced tests to avoid unnecessary procedures.

Finasteride 1 mg/day reduces semen quality without affecting hormones or sexual function.

Blocking testosterone action may improve breathing during NREM sleep in healthy men.

The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.

Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Topical testosterone can cause acne-like skin changes.

Oral mini-pulse methylprednisolone is an effective and safe treatment for alopecia areata.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.