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A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.

Finasteride, a drug used for anti-hyperplasia, can be effectively delivered in the form of matrix tablets.

Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.

Human liver enzyme DHEA ST helps process minoxidil.

Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Methotrexate is effective for treating rheumatoid arthritis but requires regular monitoring.

17b-Estradiol in skin affects hair growth and tumor promotion.

Betamethasone activates and increases the growth of certain skin cells from hair follicles.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

A new compound shows promise as a topical treatment for hair loss.

Lower doses of dexamethasone can safely reduce high DHEAS levels in women with androgenic disorders.

A small BOTOX dose improved sperm production and movement in older mice.

Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

Testosterone and finasteride improve muscle strength and size after spinal cord injury.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

A woman developed male characteristics after using unregulated hormone therapy.

Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.