15 citations
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May 2009 in “Steroids” Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.
3 citations
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January 2018 in “Reproduction, Fertility and Development” Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
50 citations
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May 2000 in “Fertility and Sterility” Flutamide reduces hair growth better but has more side effects.
4 citations
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August 2022 in “The Scientific World Journal” Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.
5 citations
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July 2021 in “medRxiv (Cold Spring Harbor Laboratory)” Proxalutamide significantly lowered hospitalization rates in women with mild-to-moderate COVID-19.
37 citations
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September 2003 in “Journal of Medicinal Chemistry” A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
1 citations
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March 2017 in “European Journal of Cancer Prevention”
44 citations
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August 1996 in “Drugs & Aging” Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
25 citations
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August 2015 in “Molecules” Mimosine dipeptides are promising for treating hyperpigmentation and inflammation.
October 2024 in “Clinical and Experimental Dermatology” The combination treatment didn't work better than minoxidil alone and caused more menstrual issues.
May 2024 in “Reactions weekly”
16 citations
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March 2020 in “Journal of The American Academy of Dermatology” Oral bicalutamide is safe and effective for female hair loss.
49 citations
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October 1994 in “Annals of Oncology” Minoxidil not effective in preventing chemotherapy-induced hair loss.
February 2026 in “European Urology”
9 citations
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November 2004 in “Bioorganic & Medicinal Chemistry Letters” New compounds were made that effectively block enzymes related to prostate issues and hair loss.
November 2022 in “Journal of the Endocrine Society” Taking biotin can lead to incorrect low results in free testosterone tests.
January 2026 in “Frontiers in Pharmacology” Certain drugs can cause male infertility, so fertility counseling and sperm preservation are advised.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” LX-38 is a safer drug option for hair loss and prostate issues without hormonal side effects.
53 citations
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June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
9 citations
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August 1992 in “The Journal of Clinical Endocrinology and Metabolism” 19 citations
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March 1994 in “Fertility and sterility” The combination therapy reduced hirsutism in women with PCOD and was well-tolerated.
1 citations
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January 2002 in “PubMed” PM-9, like finasteride, may help treat certain diseases by blocking a key enzyme.
Minoxidil may harm male reproductive health by causing testicular damage and hormonal disruption.
9 citations
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April 2018 in “JAMA Dermatology” Topical minoxidil improves hair loss in 80% of women with breast cancer undergoing endocrine therapy.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
78 citations
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October 2003 in “Cochrane library” Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.
January 2025 in “International Journal of Pharmacology” Both steroids, especially cyproterone acetate, harm quail's vital organs.
88 citations
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June 2016 in “Human Reproduction Update” New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.
1 citations
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January 2011 in “Journal of Human Reproductive Sciences” Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.