April 2024 in “Frontiers in pharmacology” Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
April 2017 in “Journal of Investigative Dermatology” SM04755 may be an effective topical treatment for psoriasis.
March 2024 in “Journal of medicinal plants studies” Hibiscus has medicinal benefits but can be toxic in high doses and is unsafe for pregnant women and infants.
October 2022 in “Biomolecules” Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
4 citations
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December 2021 in “Applied sciences” Micro-needling with low-level light therapy effectively increases hair growth in people with mild to moderate hair loss.
February 2019 in “International journal of research in dermatology” The combined treatments were highly effective for improving atrophic acne scars.
June 2026 in “Revista Brasileira de Saúde” The scalp microbiome may be a key factor in treating hair loss.
February 2023 in “Aesthetic Cosmetology and Medicine” Medicinal plants in nutricosmetics contain compounds that can improve skin and hair health.
28 citations
,
August 2019 in “BMC Genetics” miR-148a and miR-10a affect hair growth in Hu sheep.
October 2025 in “Editora Pasteur eBooks” Peptides improve skin health and treatments for hair loss and pregnancy-related skin issues are evolving.
45 citations
,
August 2019 in “Dermatologic Therapy” Hair loss treatments work better with lifestyle changes.
19 citations
,
September 2014 in “British Journal of Dermatology” Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.
5 citations
,
January 2022 in “Molecular Medicine Reports” Pine bark extract helps mice grow hair by reducing inflammation and boosting growth factors.
3 citations
,
May 2021 in “Dermatologic Clinics” The document concludes that more research is needed to understand hair loss in men and to find new treatments.
May 2026 in “Frontiers in Cell and Developmental Biology” Collagen networks play a key role in hair loss and follicle miniaturization.
February 2026 in “International Journal of Web of Multidisciplinary Studies” Restoring microbial balance and using exosome therapies may help treat hair disorders like alopecia and acne.
May 2018 in “White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)” Alopecia areata may be treated by using EGCG to balance immune cells and reduce inflammation.
220 citations
,
March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
188 citations
,
March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
165 citations
,
January 2008 in “Journal of biomaterials science. Polymer ed.” The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
150 citations
,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
147 citations
,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
134 citations
,
January 2019 in “American journal of clinical dermatology” Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.
124 citations
,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
109 citations
,
December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
108 citations
,
December 2003 in “Lasers in surgery and medicine” ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.
108 citations
,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Lowering testosterone speeds up wound healing in male mice.
94 citations
,
January 2016 in “Journal of the European Academy of Dermatology and Venereology” Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
72 citations
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.