research Atypical post-finasteride syndrome: A pharmacological riddle
Finasteride and dutasteride can cause severe, lasting side effects.
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research Response to “Reply to effectiveness of dutasteride in a large series of patients with FFA in real clinical practice”
The authors suggest that 5-α-reductase inhibitors, like dutasteride, are effective in treating frontal fibrosing alopecia and should be the first-line treatment, with other options for severe cases. They also recommend further research on Janus kinase inhibitors.
research Inibição seletiva da 5α-redutase e preservação da aromatase no transplante capilar
A balanced approach using dutasteride and Serenoa repens can improve hair transplant success by protecting follicles and minimizing side effects.
research Finasteride 1 mg in alopecia: sexual dysfunction, suicidal ideation. Providing balanced information to male patients is key.
research Effectiveness of Topical Minoxidil (5%) Plus Topical Finasteride (0.1%) Fixed-Dose Combination Versus Topical Minoxidil (5%) Plus Oral Finasteride (1 Mg/Day) in Grade II-IV Androgenetic Alopecia: A Randomized, Double Blind Clinical Trial
research Effect of 5-alpha reductase inhibitors in animal models of Parkinson’s disease
5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
research Pharmacological Role and Clinical Applications of 5α-Reductase Inhibitors-Review Article for Pharmacists and Healthcare Professionals
5α-reductase inhibitors help treat prostate enlargement and hair loss but may cause side effects, requiring careful use.
research Predstanormix Duo – a new domestic combination drug for the treatment of lower urinary tract dysfunction symptoms associated with BPH.
Predstanormix Duo is a safe and effective new drug for treating urinary symptoms from BPH.
research Evaluation of Dutasteride-Loaded Liposomes and Transfersomes for Follicular-Targeting for Androgenic Alopecia Topical Treatment
Transfersomes are better than liposomes for targeting hair follicles in alopecia treatment.
research Comparative analysis of low-dose oral minoxidil with spironolactone versus finasteride or dutasteride in female androgenetic alopecia management
Both treatment combinations improved hair growth similarly and were safe.
research マストミス雌雄前立腺における5α-reductase inhibitor (Finasteride)の影響
Finasteride reduces prostate size and DHT in male mastomys but not in females.
research Botulinum Toxin A Versus Dutasteride Mesotherapy Versus Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia
research Safety and efficacy of advanced and targeted acid α-glucosidase (AT-GAA) (ATB200/AT2221) in ERT-switch nonambulatory patients with Pompe disease: preliminary results from the ATB200-02 trial
The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.
research Finasteride, 1 mg (Propecia), Is the Optimal Dose for the Treatment of Men With Male Pattern Hair Loss
research Reply to: “Very-low-dose oral minoxidil in male androgenetic alopecia: A study with quantitative trichoscopic documentation”
Low-dose oral minoxidil effectively treats mild-moderate male hair loss, alone or combined with other therapies.
research Sexual dysfunction associated with 5α-reductase inhibitors in the treatment of androgenetic alopecia: a systematic review
5α-reductase inhibitors for hair loss can cause mild, reversible sexual side effects in some men.
research The effects of acute finasteride treatment in dopamine transporter knockout mice and MK-801-treated mice
research Enabling finasteride 1 mg users to further improve hair pattern: A randomized, double-blind, placebo-controlled trial of a novel product
The new topical product combined with finasteride significantly increased hair thickness without side effects.
research Development of Ethosomes for the Topical Treatment of Androgenic Alopecia: Ethanol Effect on Dutasteride Targeting to the Hair Follicles
Ethosomes with 30% ethanol effectively deliver dutasteride to hair follicles for treating hair loss.
research Efficacy and tolerability of finasteride 1 mg in men aged 41 to 60 years with male pattern hair loss.
Finasteride 1 mg significantly improves hair growth in men aged 41 to 60 with male pattern hair loss.
research Patient satisfaction, side effects, and other reactions reported by adult men prescribed compounded, topical finasteride via a national telehealth platform: A retrospective analysis of real world data (Preprint)
Most patients were satisfied with topical finasteride, and few experienced side effects.
research Finasteride: the first 5 alpha-reductase inhibitor.
research The clinical applications of five-alpha reductase inhibitors.
Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.
research What do we know about 5-alpha reductase inhibitors?
5-alpha reductase inhibitors like finasteride and dutasteride are effective for treating enlarged prostate and male pattern hair loss.
research Effect of finasteride on adrenal steroidogenesis in men.
Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.
research Finasteride with Doxazosin to Reduce BPH Progression
research The effectiveness of finasteride and dutasteride used for 3 years in women with androgenetic alopecia
Finasteride and dutasteride effectively stop or reverse hair loss in women with androgenetic alopecia, with dutasteride being more effective for women under 50.
research Association Between 5-Alpha Reductase Inhibitor Use and The Risk of Depression: A Meta-Analysis.
Using 5-alpha reductase inhibitors may increase the risk of mild depression.
research Post-Finasteride Syndrome: An Underestimated Phenomenon
Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.
research Forum
The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.