February 2026 in “Biochemical and Biophysical Research Communications” Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
March 2026 in “Biomolecules” MicroRNAs play a key role in controlling hair growth and quality in sheep and goats.
42 citations
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
Understanding hair follicle interactions can help treat male pattern baldness.
January 2022 in “Stem cell biology and regenerative medicine” The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.
20 citations
,
July 2005 in “Experimental dermatology” The fuzzy gene is crucial for controlling hair growth cycles.
December 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The conclusion is that the dermal papilla is crucial for hair follicle regrowth, and hair follicles undergo significant structural changes in addition to cell division during regeneration.
April 2023 in “Journal of Investigative Dermatology” 2 citations
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February 2025 in “PLoS ONE” Key proteins influence wool quality by affecting hair follicle development in sheep.
1 citations
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June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Reprogramming 3D environments can create hair follicles in the lab.
April 2017 in “Plastic and reconstructive surgery. Global open” Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
3 citations
,
January 2020
April 2017 in “Journal of Investigative Dermatology” Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
Keratinocytes grew and migrated into hair follicle areas but disappeared after 15-20 days.
September 2017 in “Journal of Investigative Dermatology” Hair follicle cells change their DNA packaging during growth cycles and when grown in the lab.
71 citations
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October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” HFMs can help study hair growth and test potential hair growth drugs.
141 citations
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November 2005 in “International journal of pharmaceutics” Hair follicles may soon be used more for targeted and systemic drug delivery.
7 citations
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January 1990
97 citations
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September 2011 in “British Journal of Dermatology” The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
May 2015 in “Journal of The American Academy of Dermatology” The research shows a potential way to regenerate hair using adult cells that have been grown and guided to produce new hair fibers.
62 citations
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February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
January 2002 in “Europe PMC (PubMed Central)” The model successfully simulates human hair growth and patterns, including hair loss types.
43 citations
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December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
4 citations
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May 2009 in “Wound Repair and Regeneration” Genetically modified cells can regenerate skin and hair in rats.
4 citations
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January 2018 in “Advances in Experimental Medicine and Biology” The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
71 citations
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January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
67 citations
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July 2000 in “Proceedings of the National Academy of Sciences” The model accurately simulates human hair growth and hair loss patterns.
35 citations
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July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
April 2016 in “Journal of Investigative Dermatology” Scientists have found a way to grow hair follicles from human cells in a lab, which could help treat hair loss and skin damage.