research Microneedles meet photomedicine: emerging strategies for diagnosis and therapy of skin diseases
Microneedles combined with light therapy can improve skin disease diagnosis and treatment.
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870-900 / 1000+ results research Folate receptor β performs an immune checkpoint function in activated macrophages
Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.
research The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review
Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
research In Patients With Acne Vulgaris, How Do Standard Acne Treatments Combined With Adjunct Microbiome-Targeted Therapies Compare to Standard Acne Treatments Alone in Affecting Clinical Outcomes?
Adding oral probiotics to standard acne treatments improves results and reduces side effects.
research Editors' Picks
Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
research The role of inflammation and immunity in the pathogenesis of androgenetic alopecia.
Inflammation and immunity play a key role in androgenetic alopecia, with better treatment outcomes in certain immune-positive cases.
research Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients
Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
research The Gut-Brain-Skin Axis and Role of Intestinal Dysbiosis in Acne Vulgaris: Therapeutic Effects of Pro- and Prebiotic Use
Probiotics and dietary changes can help treat acne.
research Gentamicin-loaded exosomes from IMMUNEPOTENT CRP enhance healing of infected diabetic wound in mice
Gentamicin-loaded exosomes improve healing of infected diabetic wounds in mice.
research Elucidating the role of the skin and gut microbiome in the development and pathogenesis of alopecia areata
Differences in skin and gut bacteria may contribute to alopecia areata.
research Smooth muscle cell expression of a constitutive active form of human Profilin1 accelerates cutaneous wound repair
Profilin1 speeds up wound healing.
research 3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects
3D spheroid culture makes stem cells better at reducing inflammation.
research Wound Microbiota and Its Impact on Wound Healing
Wound healing is greatly affected by the types of bacteria present, which can either help or hinder the process.
research Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice
The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
research Extracellular vesicles from IFN-γ-primed mesenchymal stem cells repress atopic dermatitis in mice
Stem cell vesicles reduced eczema symptoms in mice safely.
research Coordinated inhibition of SOX9 and cell cycle progression by microRNA-200 restricts sebaceous gland fate specification
MicroRNA-200 prevents sebaceous gland development by inhibiting SOX9 and cell cycle progression.
research Cutaneous immunopathology of androgenetic alopecia.
Inflammation, possibly triggered by a specific bacteria and activated by UV radiation, may contribute to male pattern baldness.
research Interdisciplinarity traditional Chinese medicine microneedles in skin disease treatment: Recent advances and challenges
Combining traditional Chinese medicine with microneedles shows promise for effectively treating skin diseases with fewer side effects.
research Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata
Early intervention with JAK inhibitors may prevent alopecia areata progression.
research MicroRNA-205 promotes hair regeneration by modulating mechanical properties of hair follicle stem cells
MicroRNA-205 helps hair regrow by making hair follicle stem cells less stiff.
research Minoxidil downregulates Interleukin-1 alpha gene expression in HaCaT cells
Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.
research MicroRNA-22-3p suppresses hair regrowth in androgenetic alopecia by targeting chloride intracellular channel 4
MicroRNA-22-3p hinders hair regrowth in male pattern baldness by affecting a specific protein.
research Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease
BTNL proteins help control inflammatory bowel disease by maintaining specific immune cells.
research Роль внеклеточных нуклеиновых кислот в процессах регенерации
Extracellular nucleic acids help start inflammation needed for tissue repair, but must be properly regulated.
research Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial Transcriptomics
Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.
research Overexpression of protein kinase C-α in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-α expression but not tumor promotion
Overexpressing PKCα in mice skin increases inflammation but doesn't affect tumor growth.
research Interleukin 6: insights to its function in skin by overexpression in transgenic mice.
Interleukin 6 may help protect skin without causing inflammation.
research Immune Microenvironment of Hair Follicles in Tumor Immunotherapy
Tumor immunotherapy can cause hair loss by disrupting hair follicle immunity.
research Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease
Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
research The Impact of Diet and Lifestyle on the Course of Autoimmune Diseases
Diet and lifestyle changes can help manage autoimmune diseases by reducing inflammation and supporting immune health.