research Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output
Lower allopregnanolone levels increase stress-related dopamine release in the brain.
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research Minoxidil
research Metabolic complications of glucocorticoids – Prevention by metformin
Metformin can help prevent the side effects of glucocorticoid medications on metabolism.
research The effect of spironolactone on genital skin 5α-reductase activity
Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
research Antiandrogen Treatment with Spironolactone and Linestrenol Decreases Bone Mineral Density in Eumenorrhoeic Women with Androgen Excess
Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.
research Urinary steroids in women with androgenic alopecia
Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
research Finasteride: a steroid-unsparing drug?
Adequate steroid treatment needed to limit bone loss in PMR patients.
research Agent: Minoxidil
Minoxidil helps lower severe blood pressure and promotes hair growth but can have serious side effects and must be used continuously.
research Trilostane treatment of 78 dogs with pituitary‐dependent hyperadrenocorticism
Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.
research Long-Term Treatment of Refractory Hypertensive Patients With Minoxidil
Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.
research Minoxidil specifically decreases the expression of lysine hydroxylase in cultured human skin fibroblasts
Minoxidil reduces lysine hydroxylase in skin cells.
research 13777 The off-label use of spironolactone in female pattern hair loss
GSK-36 downregulation with UTMD improves plaque stability in atherosclerosis treatment.
research Long-Term Clinical Effects, Bioavailability, and Kinetics of Minoxidil in Relation to Renal Function
research Vitamin D activates type A natriuretic peptide receptor gene transcription in inner medullary collecting duct cells
Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
research Finasteride/spironolactone
research Pharmacologic properties of minoxidil: a new hypotensive agent.
Minoxidil is a new drug that lowers blood pressure.
research In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases
Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.
research Beneficial Effects of Vitamin B12 and Aureomycin in Rats Given Large Doses of Cortisone.
Vitamin B12 and aureomycin reduce the negative effects of high doses of cortisone in rats.
research ANALÝZA KORTIZOLU VO VLASOCH – BIOMARKER AKTIVÁCIE HPA OSI
Hair cortisol levels can effectively indicate long-term hormone activity.
research Pharmacodynamics of minoxidil as a guide for individualizing dosage regimens in hypertension
research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
research Direct Vasodilators and Sympatholytic Agents
Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
research Spironolactone in dermatology: uses in acne and beyond
Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
research Expression and Activity Assay of Human Steroid 5 Alpha-Reductase Type II in CHO Cells
Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.
research Hormonal Control of Cardiac Action Potential Phase 1 Currents in the Brugada Syndrome
Androgens may increase arrhythmias in Brugada Syndrome, while Finasteride could reduce them.
research Development of an aequorin-based assay for the screening of corticotropin-releasing factor receptor antagonists
The new assay can help develop products for hair re-growth.
research Minoxidil
research Neurosteroids Involved in Regulating Inhibition in the Inferior Colliculus
Neurosteroids help balance brain signals when certain inhibitions are reduced.
research Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.