May 2023 in “Elsevier eBooks” Minoxidil, finasteride, and dutasteride are treatments for hair loss.
1 citations
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March 2023 in “Journal of the American College of Cardiology” 8 citations
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June 2023 in “European Journal of Endocrinology” The inhibitor affects androgen metabolism but not ovarian function.
28 citations
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January 2004 in “British Journal of Pharmacology” Minoxidil protects heart and improves recovery.
19 citations
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December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.
54 citations
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May 1977 in “The Journal of Pediatrics” Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.
September 2022 in “Journal of The American Academy of Dermatology” Monitoring potassium levels is important for women taking spironolactone.
109 citations
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July 1984 in “Circulation” Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.
1 citations
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September 2023 in “Dermatology online journal” Low dose oral minoxidil can help with hair growth but may cause serious heart problems, so doctors need to be careful.
19 citations
,
July 1983 in “American Journal of Kidney Diseases” Minoxidil lowers blood pressure in kids with kidney issues, but use carefully due to side effects.
November 2021 in “Elsevier eBooks” Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.
16 citations
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October 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
4 citations
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February 2019 in “PubMed” Clascoterone may be an effective topical treatment for hair loss.
August 2023 in “Journal of Cosmetic Dermatology” Both minoxidil-spironolactone and minoxidil-finasteride treatments work for hair loss, but minoxidil-spironolactone is slightly more effective, especially in women.
5 citations
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May 2025 in “Journal of the American Academy of Dermatology”
89 citations
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February 1993 in “Journal of Medicinal Chemistry” New compounds called benzoquinolinones may treat conditions linked to excess DHT.
April 2023 in “Medicina Clínica (english Edition)”
January 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil alone is effective for treating hair loss, but combining it with dutasteride or finasteride may offer better results.
3 citations
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June 2018 in “Bioorganic & medicinal chemistry” Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
Minoxidil effectively promotes hair growth in seborrheic alopecia.
September 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil does not significantly affect blood pressure in patients with hair loss and hypertension.
Spironolactone is effective and safe for treating acne.
90 citations
,
May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
27 citations
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April 1992 in “Biochemical Journal” Minoxidil reduces lysine hydroxylase in skin cells.
March 2025 in “Journal of Clinical Medicine” Low-dose oral minoxidil effectively treats alopecia but can cause side effects like excess hair growth and fluid retention.
January 2024 in “Expert Opinion on Pharmacotherapy” Low-dose oral minoxidil is effective and safe for treating hair loss in men and women.
112 citations
,
April 2009 in “Cochrane library” Spironolactone may reduce excessive hair growth in women but its effectiveness for acne is not supported.
4 citations
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December 2017 in “PubMed” Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.