66 citations
,
September 1982 in “Biochemical Pharmacology” Liver enzyme helps minoxidil work better for blood vessel relaxation.
53 citations
,
January 1993 in “Biochemical Pharmacology” Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.
48 citations
,
June 1988 in “PubMed” Minoxidil sulfate relaxes muscle by increasing potassium flow, making it a unique muscle relaxer.
47 citations
,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
39 citations
,
November 1987 in “Clinica Chimica Acta” Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.
32 citations
,
March 2013 in “Journal of Pharmaceutical Sciences” Iontophoresis improves minoxidil delivery for alopecia treatment.
32 citations
,
January 1994 in “Skin Pharmacology and Physiology” Minoxidil helps hair growth by activating enzymes in hair follicles.
16 citations
,
July 1994 in “Journal of Dermatological Science” Minoxidil sulfate and pinacidil may promote hair growth through increased blood flow, not by activating potassium channels.
13 citations
,
January 1987 in “Dermatology” Minoxidil sulfate relaxes blood vessels by increasing potassium permeability.
5 citations
,
January 2018 in “Skin appendage disorders” Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.
4 citations
,
May 2020 in “Medicine in Drug Discovery” The study developed a method to detect minoxidil and its sulfate form, found that minoxidil sulfate is temperature-sensitive, and identified a way to potentially increase its stability for hair loss treatment.
1 citations
,
January 1992 in “The Nishinihon Journal of Dermatology” Minoxidil sulfate did not enhance hair growth or cell proliferation at tested levels.
January 2026 in “Journal of Applied Polymer Science” The new fiber offers long-lasting minoxidil release and can be used in wigs for hair treatment and coverage.
April 2025 in “International Journal of Pharmaceutics” Liposomes improve minoxidil delivery to hair follicles, enhancing treatment for hair loss.
December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)” Minoxidil sulfate significantly improved hair growth in mice.
January 2008 in “Abstracts” Minoxidil sulfate gel can be used to treat hair loss.
Minoxidil sulfate, delivered through iontophoresis, can be used to treat hair loss.
11 citations
,
April 2017 in “Journal of research in pharmacy practice” The combination of zinc sulfate and calcium pantothenate effectively controls early-stage hair loss.
68 citations
,
September 1990 in “Biochemical Pharmacology” Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
59 citations
,
February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
19 citations
,
October 1989 in “PubMed” Minoxidil helps hair growth by being sulfated in hair follicles.
May 2023 in “International Journal of Trichology” A witch-hazel-based 5% minoxidil solution is effective and safe for women with hair loss who didn't respond to regular minoxidil, especially if they're sensitive to propylene glycol.
5 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Minoxidil boosts hair growth by undergoing a process in hair follicles and certain skin cells, and by increasing the production of compounds essential for hair growth and maintenance.
September 1992 in “Journal of Dermatological Science”
27 citations
,
November 2013 in “Dermatologic Therapy” New test predicts if hair loss treatment will work.
9 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Minoxidil helps hair growth by increasing blood flow and stimulating hair follicles.
7 citations
,
January 1992 in “Skin Pharmacology and Physiology” Minoxidil binds to hair pigment but doesn't affect hair growth.
4 citations
,
May 2019 in “PubMed” Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.
3 citations
,
April 2010 in “Journal of Receptors and Signal Transduction” Minoxidil, a common alopecia medication, might cause eye changes due to its properties and lack of tissue selectivity.
1 citations
,
January 1992 in “Juntendō Igaku/Juntendo igaku” Minoxidil promotes hair growth by increasing blood flow and directly affecting hair follicles.