29 citations
,
February 2018 in “European Journal of Immunology” Regulatory T cells are essential for normal and improved wound healing in mice.
29 citations
,
December 2017 in “Molecular therapy” Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
29 citations
,
October 2016 in “Cell death and differentiation” ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
29 citations
,
February 2016 in “Scandinavian journal of urology” Late puberty may slightly lower prostate cancer risk, baldness is not linked to overall risk but less so with aggressive types, ibuprofen use may increase risk, and vitamins show no effect on risk.
28 citations
,
September 2014 in “Journal of Clinical Oncology” Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.
28 citations
,
September 2013 in “Expert Opinion on Therapeutic Patents” New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
28 citations
,
March 2010 in “British Journal of Dermatology” Genetic marker rs12558842 strongly linked to male hair loss.
28 citations
,
October 2004 in “Differentiation” A gene deletion causes the "hairless" trait in Iffa Credo rats.
27 citations
,
March 2022 in “Forensic Toxicology” Micro-segmental hair analysis helps detect drug use patterns and estimate drug consumption days.
27 citations
,
January 2016 in “Quality of Life Research” The PCOSQ-50 is a valid and reliable questionnaire for measuring quality of life in Iranian women with PCOS.
27 citations
,
December 2014 in “Current problems in dermatology” Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.
27 citations
,
April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
27 citations
,
January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
26 citations
,
December 2020 in “Nature metabolism” Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
26 citations
,
July 2016 in “PLOS ONE” Activating β-catenin in certain skin cells speeds up hair growth in mice.
25 citations
,
November 2008 in “Facial Plastic Surgery” Dr. Michael Beehner recommends a personalized, careful approach to hairline design in hair replacement surgery for a natural look.
24 citations
,
July 2019 in “Cochrane library” Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
24 citations
,
May 2019 in “PLOS ONE” The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
24 citations
,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
24 citations
,
June 2012 in “BMC Research Notes” The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
24 citations
,
August 2011 in “Experimental Dermatology” The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
23 citations
,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
23 citations
,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
22 citations
,
November 2021 in “Dermatology and Therapy” The AAPPO questionnaire is a reliable tool for assessing hair loss impact in alopecia areata patients.
22 citations
,
October 2019 in “Cerebral cortex” Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
22 citations
,
March 2019 in “Environmental health” Higher fluoride levels may delay puberty in boys.
22 citations
,
January 2017 in “Advanced Healthcare Materials” The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.
21 citations
,
May 1996 in “Current problems in dermatology” Detailed patient history and physical exams are crucial for diagnosing hair loss.
21 citations
,
January 2018 in “PLoS Genetics” Certain genetic variants in keratins increase the risk of tooth decay.
21 citations
,
May 2017 in “International Journal of Dermatology” Overweight smokers have worse hair loss.