March 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Combining nonablative fractional laser with minoxidil was effective for alopecia areata with only one patient relapsing after a year.
October 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Adding dalteparin and protamine microparticles to platelet-rich plasma can boost hair growth more than using platelet-rich plasma alone.
December 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” There are several promising treatments for hair loss, including dutasteride, latanoprost, ketoconazole shampoo, anti-androgens, laser/light treatment, and platelet-rich plasma, but more research is needed.
October 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” August 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
February 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Low-dose oral minoxidil is a promising, safe treatment for various hair diseases, improving hair thickness and density, but more research is needed on long-term side effects and treatment duration.
July 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” June 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
January 2017 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” 60% of women who didn't respond to 5% minoxidil for hair loss showed significant improvement with a 15% minoxidil solution.
May 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
February 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A hair test can accurately predict if a person with hair loss will respond to minoxidil treatment.
December 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Low-level light therapy significantly increased hair density and thickness in people with hair loss, but they didn't notice a difference.
July 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Applying valproic acid on the scalp increased hair growth in men with hair loss.
February 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Dutasteride 0.5mg is more effective than finasteride 1mg for treating male pattern baldness.
Hair loss at the top of the head is linked to prostate cancer, but other types of hair loss are not.
9 citations
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November 2007 in “Blood” TMPRSS6 is crucial for controlling hepcidin and normal iron absorption.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.
15 citations
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February 2021 in “Scientific Reports” RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
April 2019 in “Journal of Investigative Dermatology” Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
15 citations
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April 2019 in “Journal of Cellular Biochemistry” Certain blood miRNAs are linked to severe alopecia areata and could lead to new treatments.
October 2014 in “Cancer research” Blocking mTORC1 reduces skin tumor growth in mice.
15 citations
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March 2021 in “EMBO Reports” PRSS35 enzyme may help start skin tumors and could be a target for cancer treatment.
April 2023 in “Journal of Investigative Dermatology” AL136131.3 slows hair growth by affecting energy processes in hair loss.
46 citations
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May 1995 in “Proceedings of the National Academy of Sciences” A specific gene region can control targeted and responsive gene expression in mice, useful for skin disorder treatments.
10 citations
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July 2021 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” LRIG1 is linked to better survival in Merkel cell carcinoma.
21 citations
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August 2007 in “Experimental Dermatology” Overexpression of hurpin in mice leads to abnormal skin and higher skin cancer risk.
31 citations
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June 2022 in “Stem Cell Research & Therapy” CD146 + mesenchymal stem cells are more effective for treating premature ovarian failure.
April 2026 in “Human Genome Variation” The MBTPS2 gene variant c.970+5G>A is a common mutation causing IFAP syndrome.
15 citations
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November 2022 in “Cell Death and Disease” CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.