research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
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research Investigating RNA-Seq-based differential gene expression during hair follicle development in Angora goat skin
Angora goat hair growth is influenced by gene expression, sex hormones, and breed differences.
research Vitamin D Receptor Gene Polymorphism In Chronic Telogen Effluvium; A Case-Control Study
Certain gene variations in the Vitamin D receptor may increase the risk of chronic hair loss.
research The evaluation of IL-4 VNTR intron 3 and TNF-α (rs1799964) gene polymorphisms in Egyptian patients with alopecia areata: a case–control study
These gene variations are not linked to alopecia areata in Egyptians.
research Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research Transcriptome Dynamics Reveal Stage-specific and Melatonin-triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.
research Exosomes as a novel pathway for regulating development and diseases of the skin (Review)
Exosomes are important for skin health and could help diagnose and treat skin diseases.
research Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues
The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.
research Keratin-mediated hair growth and its underlying biological mechanism
Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
research Androgen receptor gene polymorphism and biological age markers in men
AR gene variations don't affect aging markers in men.
research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid LupusErythematosus by Weighted Gene Co-Expression Network Analysis
Key genes linked to immune response are upregulated in hair follicles and skin tissues in chronic discoid lupus erythematosus.
research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid Lupus Erythematosus by Weighted Gene Co-Expression Network Analysis
Key genes linked to immune response are highly active in lupus-affected hair follicles.
research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Microneedles mediated bioinspired lipid nanocarriers for targeted treatment of alopecia
A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
research From bedside to bench: regulation of host factors in SARS-CoV-2 infection
The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.
research Gene Therapy: Recent Advances and Applications in Dermatology
Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.
research GPCRs as key regulators in wound healing
GPCRs are vital for wound healing by affecting cell growth and immune response.
research Effects of FGF5-mediated LncRNA on the skin fibroblast growth of Liaoning Cashmere goats
FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.
research Regulation of VDR by ΔNp63α is associated with inhibition of cell invasion
ΔNp63α helps control a protein that stops cancer cells from spreading.
research Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies
Hormones and genes affect hair growth and male baldness.
research Analysis of gene expression patterns and levels in maize hybrids and their parents
Maize hybrids show better early growth due to complex gene interactions from their parent strains.
research Regulation of hair follicle development by exosomes derived from dermal papilla cells
Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
research Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia
Birds can regenerate inner ear cells using specific gene pathways, unlike mammals.
research Ovarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome
Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
research CD98hc (SLC3A2) regulation of skin homeostasis wanes with age
CD98hc's role in skin health decreases with age.
research Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research 5α-Reductase isozymes and aromatase mRNA levels in plucked hair from young women with female pattern hair loss
Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
research Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice
Increasing Wnt5a in mice skin delays hair growth but doesn't stop it.
research Wnt4 is crucial for cardiac repair by regulating mesenchymal-endothelial transition via the phospho-JNK/JNK
Wnt4 is essential for heart repair and could be a target for heart disease treatment.
research Anticytokine therapy, particularly anti-IFN-γ, in Th1-mediated autoimmune diseases
Blocking interferon-gamma might help treat various autoimmune diseases.