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Mouse genital development depends on male or female hormones for specific features.

The document concludes that facial feminization surgery improves psychological well-being and social acceptance for transgender individuals.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Transgender and nonbinary individuals experience hair loss, with transmen on testosterone seeing more severe hair loss, while feminizing hormones may stabilize hair loss in transwomen.

Hormonal therapy for transgender individuals carries health risks but is a personal choice.

A woman developed male characteristics after using unregulated hormone therapy.

Progesterone may help trans women with breast development and health, but more research is needed.

Lip feminization is important for transgender women, requiring personalized approaches and expert consultation for best results.

Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Hormone therapy in transgender women can affect hair growth and acne, and there are specific skin issues related to gender-affirming surgery, but more research is needed on their dermatological health.

Few dermatology programs mention gender-affirming care, highlighting a need for better training and visibility.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Hair transplants help transgender patients look more like their gender identity, with different procedures for trans women and men.

Hormonal therapy in transgender patients can lead to skin changes like altered sebum production, hair growth, and acne, which may require dermatological care.

A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.

Estrogen alone may effectively suppress testosterone in some transfeminine individuals.

Proper management of the dilation program is crucial after male-to-female reassignment surgery.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Transgender patients face more barriers to oral healthcare, leading to poorer oral health and quality of life.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Australia needs better dermatological guidelines for gender-diverse patients.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.