Androgenetic Alopecia in Transgender and Gender Diverse Populations: A Review of Therapeutics

    Julia Gao, Carl G. Streed, Julie D. Thompson, Erica D. Dommasch, Jon K. Peebles
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    TLDR The document concludes that treatments for hair loss in transgender and gender-diverse individuals include topical solutions, oral medications, laser therapy, and hair restoration procedures, with progress assessed after 6-12 months.
    The document reviews treatments for Androgenetic Alopecia (AGA) in transgender and gender-diverse patients. First-line treatments include topical minoxidil 5%, finasteride 1 mg, low-level laser light therapy, and for transfeminine patients, spironolactone 200 mg. Second-line options include oral minoxidil (1.25 mg for transfeminine and 2.5 mg for transmasculine patients), topical finasteride 0.25% alone or with minoxidil 2%, oral dutasteride 0.5 mg, platelet-rich plasma, or hair restoration procedures. Treatment progress should be assessed after 6-12 months using non-sex-based scales like the Basic and Specific Classification or the Bouhanna scales. Dermatologists should coordinate with the patient's primary gender-affirming clinician(s) to ensure shared knowledge of all medications.
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      community Hair Growth Caps and Helmets Research

      in Research/Science  28 upvotes 1 month ago
      Hair growth caps and helmets using low-level laser therapy (LLLT) show potential for treating androgenetic alopecia, but more research is needed. Users often combine these devices with treatments like minoxidil and finasteride for better results.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 1 year ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community 5-Months Update: Minoxidil + Red Light Therapy + Lifestyle Changes

      in Progress Pictures  1031 upvotes 1 year ago
      The user reported positive hair regrowth after 5 months using Minoxidil, red light therapy, and lifestyle changes, including dietary improvements and stress reduction. They chose natural supplements like saw palmetto and beta-sitosterol over pharmaceutical DHT inhibitors like finasteride.

      community My Theory Of Androgenic Alopecia

      in Research/Science  19 upvotes 4 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

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