5 citations
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January 2021 in “iScience” Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
138 citations
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November 2015 in “Journal of Pharmacology and Experimental Therapeutics” Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
65 citations
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September 2010 in “Journal of the Neurological Sciences” Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
26 citations
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February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
19 citations
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September 2014 in “British Journal of Dermatology” Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.
1 citations
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November 2025 in “Cell Death and Disease” Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.
41 citations
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September 2010 in “Journal of dermatological science” Bone marrow and umbilical cord stem cells can help grow new hair.
17 citations
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April 2023 in “Aging” CNGA3, GLUD1, and SIRT1 are promising targets for treating aging and glioblastoma.
13 citations
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December 2024 in “Cellular and Molecular Life Sciences” Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
2 citations
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March 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.
1 citations
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April 2021 in “Current Stem Cell Reports” Eating less can improve stem cell function and increase lifespan.
97 citations
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September 2006 in “Pharmaceutical Research” No treatment fully prevents hair loss from chemotherapy yet.
38 citations
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September 2021 in “Signal Transduction and Targeted Therapy” Genetic differences affect COVID-19 severity and treatment development.
3 citations
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May 2024 in “Amino Acids” Disrupted cysteine metabolism may cause hair breakage in Alopecia Areata, suggesting potential treatments like N-acetylcysteine.
Wild African goats have genetic adaptations for surviving harsh desert conditions.
506 citations
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January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
474 citations
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January 2012 in “Chemistry & biology” Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
421 citations
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January 2015 in “Chemical Society Reviews” Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
369 citations
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June 2013 in “Biochimie” Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
343 citations
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December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
306 citations
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April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
253 citations
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March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
170 citations
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September 2019 in “Evidence-based Complementary and Alternative Medicine” Some medicinal plants can help heal wounds and may lead to new treatments.
161 citations
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August 2013 in “Journal of experimental botany” Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.
150 citations
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April 2013 in “Dermato-endocrinology” Estrogen therapy can reduce skin aging but has cancer risks.
144 citations
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August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
144 citations
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March 2013 in “Circulation Research” K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
130 citations
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August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
129 citations
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January 2019 in “Clinical medicine insights” Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.