research Essential resources and best practices for laboratory mouse research
Use ethical and humane practices in mouse research.
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840-870 / 1000+ resultsresearch Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease
Zebrafish are useful for studying and developing treatments for human skin diseases.
research Can an in vitro hair drug model be developed using dermal papilla cells alone?
Dermal papilla microtissues could be useful for initial hair growth drug testing.
research Dynamic evaluation of pathological changes in a mouse acne model by optical imaging technology
New imaging techniques can assess and track changes in mouse acne without harm, aiding treatment choices.
research Thermodynamic Modeling of the Gas-Antisolvent (GAS) Process for Precipitation of Finasteride
The Gas-Antisolvent process can be effectively modeled and optimized to create Finasteride, a hair growth drug.
research Dose-dependent and long term effects of RU58841 (androgen receptor blocker) on hair growth in the bald stumptailed Macaque.
RU58841, an androgen receptor blocker, significantly increased hair density, thickness, and length in monkeys when applied topically daily for several months.
research An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis
Basement membrane changes are crucial for hair follicle development.
research Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence
Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome
Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
research Assessment of Multidimensional Health Care Parameters Among Adults in Japan for Developing a Virtual Human Generative Model: Protocol for a Cross-sectional Study
The study aims to create a model to predict health attributes using diverse health data from Japanese adults.
research Cell Population Dynamics in Wound-Induced Hair Follicle Neogenesis Model
Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.
research A Study on the Development of a Web Platform for Scalp Diagnosis Using EfficientNet
A web platform was created to help diagnose scalp conditions accurately and easily.
research Dose‐response of human follicles during laser‐based hair removal: Ex vivo photoepilation model with classification system embracing morphological and histological features
Higher light doses cause more damage to hair follicles, predicting better hair removal results.
research Apremilast and tofacitinib exert differential effects in the humanized mouse model of alopecia areata
Tofacitinib was more effective than apremilast in treating hair loss in a mouse model of alopecia areata.
research Modeling share dynamics by extracting competition structure
The model can predict website market shares by identifying competition among them.
research Harmonic Vibrational Frequency Simulation of Pharmaceutical Molecules via a Novel Multi-Molecular Fragment Interception Method
The new method provides more accurate vibrational frequencies for drug molecules than traditional models.
research Human hair follicle-derived mesenchymal stem cells promote tendon repair in a rabbit Achilles tendinopathy model
Human hair follicle stem cells help repair tendon injuries.
research Antiepileptogenic effects of trilostane in the kainic acid model of temporal lobe epilepsy
Trilostane may help delay epilepsy development by increasing certain brain chemicals.
research Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles
ASC-CM is more effective than EV for treating osteoarthritis.
research Evaluation of Antiarthritic and Antinociceptive Effects of Cedrol in a Rat Model of Arthritis
Cedrol may help treat rheumatoid arthritis due to its anti-inflammatory and antioxidant effects.
research In-vitro permeation of drugs into porcine hair follicles: is it quantitatively equivalent to permeation into human hair follicles?
Porcine hair follicles can effectively model human hair follicles for drug absorption.
research Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome
Replacing defective mesenchymal cells with normal ones fixes thymic growth issues in 22q11.2DS mouse models.
research Biomechanics of hair fibre growth: A multi-scale modeling approach
The model shows that factors like follicle shape and stiffness are key for hair growth and anchoring.
research Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort
Fluconazole can cause hair loss, but the exact cause is unknown.
research Immune Cells in Cutaneous Wound Healing: A Review of Functional Data from Animal Models
Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.
research XMU-MP-1 induces growth arrest in a model human mini-organ and antagonises cell cycle-dependent paclitaxel cytotoxicity
XMU-MP-1 stops cell growth in a human mini-organ and reduces the effectiveness of the chemotherapy drug paclitaxel.
research Multimodal imaging of hair follicle bulge-derived stem cells in a mouse model of traumatic brain injury
Hair follicle stem cells might help treat traumatic brain injury.
research Induction of ornithine decarboxylase activity in hairless rat epidermis as a pharmacological model: validation of the animal model
Female rats aged 8 weeks are best for this model.
research Primary TSC2-/meth Cells Induce Follicular Neogenesis in an Innovative TSC Mouse Model
TSC2-/meth cells can cause skin lesions, hair growth, and lung issues, and may be treated with chromatin remodeling agents.
research Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects
A topical BRAF inhibitor, vemurafenib, can speed up wound healing and promote hair growth, especially in diabetic patients.