research 1250 Development of an ex vivo human skin explant model to examine candidate gene functions in the hair follicle and epidermis
The model can effectively test gene functions and drug responses in human skin.
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research Reversal of alopecia areata in a mouse model of human hair loss by daily dietary administration of a proprietary extract of North American ginseng (Panax Quinquefolius)
North American ginseng extract helped regrow hair in balding mice.
research Experimental models to investigate the efficacy and bioequivalence of low dose topical corticoids
Patients with systemic lupus erythematosus and hair loss had fewer hair follicles and non-scarring alopecia; direct immunofluorescence was not helpful in diagnosing lupus in these cases.
research 3D‐Printed Hydrating Masque for Diabetic Wounds Repair: A Nitric Oxide‐Enhanced Tremella Polysaccharide‐Based Scaffold for Improved Wound Comprehensive Regulation
A 3D-printed masque helps diabetic wounds heal faster by reducing inflammation and promoting skin regeneration.
research The Role of miR-214-3p in Hair Follicle Neural Crest Stem Cell-derived Exosomes in the Repair of Peripheral Nerve Injury
miR-214-3p helps nerve repair and recovery.
research The Role of miR-214-3p in Hair Follicle Neural Crest Stem Cell-derived Exosomes in the Repair of Peripheral Nerve Injury
miR-214-3p helps nerve repair and recovery.
research EXERCISE-INDUCED EXTRACELLULAR VESICLES DELAY TUMOR DEVELOPMENT VIA IGNITING THE INFLAMMATION IN THE IMMUNOLOGICALLY COLD BREAST CANCER MODEL
Exercise-induced particles can slow breast cancer growth by boosting immune response.
research 308 Epidermal keratinocytes regulate bacterial immune responses and host defense through EGFR
EGFR inhibitors cause skin issues and hair loss by weakening skin defenses, suggesting antibiotics and targeted treatments can help.
research 309 DOES VARIATION IN EITHER AGE AT START OF THERAPY OR DURATION OF THERAPY MAKE CHEMOPREVENTION WITH FINASTERIDE COST-EFFECTIVE?
Starting finasteride at age 65 and continuing until age 80 is the most cost-effective strategy for prostate cancer prevention.
research GSK-3 Inhibitors: Recent Developments and Therapeutic Potential
Drugs that block GSK-3 show promise for treating various diseases.
research MicroRNA-22-3p suppresses hair regrowth in androgenetic alopecia by targeting chloride intracellular channel 4
MicroRNA-22-3p hinders hair regrowth in male pattern baldness by affecting a specific protein.
![Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment](/images/research/693e7bf6-2325-4ddc-a20f-3470db9f4516/small/25627.jpg)
research Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment
A new topical treatment for hair loss shows strong hair growth effects with low toxicity.
research Current Biomedical Applications of 3D-Printed Hydrogels
3D-printed hydrogels show promise in medicine but face challenges in resolution, cell viability, cost, and regulations.
research A Mouse Model for Studying Stem Cell Effects on Regeneration of Hair Follicle Outer Root Sheaths
The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
research An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice
Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.
research Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model
IGF2BP3 and other m6A-related genes are linked to keloid formation and could be potential treatment targets.
research Evaluating anti-LGBTQIA+ medical bias in large language models
Large language models often give biased or inaccurate medical responses, especially for LGBTQIA+ prompts.
research Histological Study of Skin Aging Model Treated with Topical Mesenchymal Stem Cell-Conditioned Medium
MSC-CM cream may help repair and improve aging skin.
research Advances and Innovations of 3D Bioprinting Skin
3D bioprinting shows promise for creating advanced skin for healing wounds and reducing animal testing.
research A texture-driven model for male baldness
The document concludes that the new model realistically simulates male baldness and could be useful for medical purposes and entertainment.
research PVA based nanofiber containing CQDs modified with silica NPs and silk fibroin accelerates wound healing in a rat model
The nanofiber dressing speeds up wound healing and hair growth while preventing bacterial growth.
research Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures
A new 3D culture system helps grow and study mouse skin stem cells for a long time.
research 3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis
3D bioprinting with special hydrogels helps heal wounds and grow new blood vessels.
research Morphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epithelium
FoxN1 gene is essential for proper thymus structure and preventing hair loss.
research 3D-printed porous functional composite scaffolds with polydopamine decoration for bone regeneration
The scaffold with polydopamine and bioactive glass effectively promotes bone regeneration.
research 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes
A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
research 3D printing sequentially strengthening high-strength natural polymer hydrogel bilayer scaffold for cornea regeneration
A new 3D-printed hydrogel scaffold helps regenerate corneas and prevent scarring.
research RETRACTED ARTICLE: Up-regulated lncRNA5322 elevates MAPK1 to enhance proliferation of hair follicle stem cells as a ceRNA of microRNA-19b-3p
A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.
research DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages
DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
research IGF2BP2 and IGFBP3 Genotypes, Haplotypes, and Genetic Models Studies in Polycystic Ovary Syndrome
Certain genetic variations in IGF2BP2 and IGFBP3 are linked to a higher risk of PCOS.