research Identification of Drug-Disease Associations Using Information of Molecular Structures and Clinical Symptoms via Deep Convolutional Neural Network
A new model can predict drug-disease links well, helping drug research.
Search
for
Sort by
Research
660-690 / 1000+ results research Selenium Compounds and Their Bioactivities: Molecular Mechanisms and Prospects for Functional Food and Therapeutic Applications
Selenium from plants is beneficial and safer for health.
research The antiviral activity of a small molecule drug targeting the NSP1-ribosome complex against Omicron, especially in elderly patients
Golvatinib shows promise as a treatment for Omicron in elderly patients.
research Integrating proteomics revealed the key targets for molecular breeding of fine cashmere traits in cashmere goats
Key proteins affecting cashmere fiber quality were identified for better breeding.
research Comparative proteomic analysis of male and female androgenetic alopecia: elucidating gender-specific molecular patterns
Male and female pattern hair loss have different molecular pathways, suggesting unique treatment targets for each sex.
research Synthesis and application of clinically approved small-molecule drugs targeting androgen receptor
Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
research Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions
One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.
research Geographical Differences in Male Infertility between the United States and Canada: Insights from the Andrology Research Consortium
American men are older, more obese, and have longer infertility than Canadian men.
research GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states
GRHL3 is important for controlling gene activity in skin cells during different stages of their development.
research Dynamic changes of genomic methylation profiles at different growth stages in Chinese Tan sheep
DNA methylation changes in Tan sheep affect growth and fur traits.
research The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Whole-genome resequencing to investigate the genetic diversity and the molecular basis underlying key economic traits in indigenous sheep breeds adapted to hypoxic environments
Tibetan sheep have specific genes for high-altitude adaptation and wool traits, aiding breeding strategies.
research Comparative Evaluation of Wound Healing Effect of Cord Blood Low Molecular Weight Fraction (Below 5 kDa) and Actovegin Drug in Skin Cryolesions
Cord blood fraction heals skin wounds as effectively as Actovegin.
research Signal Peptide-CUB-EGF-like Domain-Containing Protein 3 (SCUBE3): From Molecule to Therapy
SCUBE3 is a potential target for cancer and alopecia treatment but is challenging to target due to its varied roles.
research Comparative Analysis of Chloroplast Genomes in Sansevieria Reveals Phylogenetic Relationships and High Variability Molecular Markers
Sansevieria and Dracaena are evolutionarily linked, and a specific gene marker can distinguish closely related species.
research Ex vivo SIM-AFM measurements reveal the spatial correlation of stiffness and molecular distributions in 3D living tissue
Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.
research ISX9, a small molecule targeting Axin, activates Wnt/β-catenin signaling and promotes hair regrowth
ISX9 helps regrow hair by activating a specific cell signaling pathway.
research Birt–Hogg–Dubé syndrome: from gene discovery to molecularly targeted therapies
New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
research Multiomics-empowered Deep Phenotyping of Ulcerative Colitis Identifies Biomarker Signatures Reporting Functional Remission States
Microvascular damage and platelet issues persist in ulcerative colitis remission, helping assess disease states.
research Platelet-Rich Plasma (PRP) in Dermatology: Cellular and Molecular Mechanisms of Action
PRP therapy helps skin heal and improve by promoting cell growth and repair.
research Genome-Wide Associations with Body and Fleece Weight in United States Sheep
Certain genetic markers can help predict wool production in U.S. sheep.
research Carbonylation of hair proteins: A robust biomarker of molecular and structural oxidative damage in hair fibres
Protein carbonylation is a sensitive marker for oxidative damage in hair, especially from light exposure.
research Sexual steroid regulation of spermatogenesis: new actors enter the stage
Estrogens and androgens are crucial for male fertility.
research Platelet-rich plasma as a site-targeted approach in wound healing: a molecular perspective
Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.
research Biliary fibrosis is an important but neglected pathological feature in hepatobiliary disorders: from molecular mechanisms to clinical implications
Biliary fibrosis is crucial in liver diseases and understanding it can help prevent and treat these conditions.
research Anti-Alopecia Activity of Alkaloids Group from Noni Fruit against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies
Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.
research A New Office Based Protocol to Reverse AGA Miniaturization at Early and Advanced Stages
New treatment effectively reverses hair thinning in most patients with mild side effects.
research Exploring the Antioxidative Effects of Ginger and Cinnamon: A Comprehensive Review of Evidence and Molecular Mechanisms Involved in Polycystic Ovary Syndrome (PCOS) and Other Oxidative Stress-Related Disorders
Ginger and cinnamon can help manage PCOS and related disorders by reducing oxidative stress and inflammation.
research Advances in Nanocarrier Systems for Dermatologic Transdermal Drug Delivery: A Chemical and Molecular Review
Nanocarriers show promise for improving skin drug delivery in treating skin conditions.
research Online Survey on Perceptions and Practices of Hair Oiling Among Diverse Demographics in the Southern States of India
Hair oiling is popular in southern India, but some people experience scalp issues, indicating a need for better guidance.