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The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Women with PCOS are more likely to suffer from depression, anxiety, and stress.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Some common medications can harm male fertility, but many effects can be reversed.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Hormonal therapies are safe and effective for treating adult women's acne.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Red-light therapy may slow myopia progression better than traditional treatments.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.