26 citations
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August 2004 in “Alcoholism Clinical and Experimental Research” Ethanol-induced motor incoordination in rats is not affected by increased neuroactive steroids.
24 citations
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June 2020 in “Dermatologic Therapy” New drugs like N-acetylcysteine and dronabinol show promise for treating hair-pulling disorder.
3 citations
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June 2023 in “Medicina” No medications for alcohol dependence have been approved for marketing yet.
63 citations
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August 1996 in “Forensic Science International” Cosmetic treatments like bleaching and perming can greatly reduce opiate levels in hair, possibly leading to false-negative drug tests.
January 2012 in “Medizinisch Wissenschaftliche Verlagsgesellschaft eBooks”
123 citations
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December 2015 in “Journal of Neuroendocrinology” New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
Lower DHT and higher testosterone levels increase brain activation but don't change behavior in heavy drinkers.
15 citations
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March 2007 in “Hormones and Behavior” Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.
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June 2015 in “Journal of anatomy” A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
52 citations
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April 2002 in “Brain Research” Lower allopregnanolone levels increase stress-related dopamine release in the brain.
2 citations
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November 2024 in “JAAD reviews.” Certain drugs can change hair color, either lightening or darkening it.
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May 2009 in “Journal of Neuroscience” In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
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April 2015 in “Advances in Psychosomatic Medicine” Psychotropic medications can cause skin problems but also treat some skin conditions.
Anesthetizing walruses is difficult and risky due to their size and sudden health changes.
October 2011 in “The American Journal of Gastroenterology” Methadone may worsen liver fibrosis in males with HCV.
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September 2010 in “Stress” Neurosteroids help protect fetal brains from asphyxia damage.
April 2025 in “JAAD reviews.” Skin issues can signal substance use, helping early detection and treatment.
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June 2019 in “Psychoneuroendocrinology” Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
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February 2017 in “Journal of neuroscience research” Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.
January 2012 in “The Year book of dermatology” Finasteride 5mg/day improves hair loss in normoandrogenic Asian women.
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April 2011 in “Neuropharmacology” 11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.
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May 2016 in “Progress in Neuro-Psychopharmacology and Biological Psychiatry” Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.
November 2019 in “Synapse” Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
54 citations
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August 2005 in “Alcohol” Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.
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December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
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April 1987 in “American Journal of Nursing” Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.
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July 2006 in “Neuropsychopharmacology” 20 citations
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August 2017 in “Drug testing and analysis” Drugs localize differently in hair strands based on their properties.
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July 2015 in “Frontiers in Cellular Neuroscience” Corticosterone makes ethanol more effective at blocking brain processes important for learning and memory.
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September 2011 in “Pain” PEA reduces pain by increasing neurosteroid synthesis in the spinal cord.