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Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Stopping minoxidil and using prostaglandin analogues improved the man's eye condition.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

High levels of male hormones in women with PCOS can lead to fertility issues and symptoms like irregular periods, hair growth, acne, and hair loss; lifestyle changes are recommended for management.

Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.

Progesterone-derived neurosteroids affect GABA-A receptor expression, influencing epilepsy during menstrual cycles.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.

Agmatine may help reduce seizures linked to hormone changes in female rats.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

A 20-year-old woman was found to have a rare ovarian tumor causing symptoms like acne and a low-pitched voice, which disappeared after the tumor was removed.

Medroxyprogesterone acetate is as effective as oral contraceptives for resuming ovulation in women with PCOS.

Estrogen treatments can cause unwanted effects in men and should be used cautiously.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

A postmenopausal woman's high testosterone levels and symptoms improved after removing a tumor from her ovary.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Ovarian and stress hormones can change GABA A receptors through neurosteroids.

Flibanserin may help improve sexual symptoms in various conditions beyond its approved use.

In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.

Leydig cell tumors can cause high testosterone and symptoms like hair loss in postmenopausal women, but surgery can improve these symptoms.

Estrogen alone may effectively suppress testosterone in some transfeminine individuals.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.

Progesterone and allopregnanolone increase glycine release in rat brain cells.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.