November 2025 in “Journal of Investigative Dermatology” Alpha-MSH affects mitochondrial function, and MC1R mutations may increase skin aging.
February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair follicles protect melanocytes from sun damage, helping them replenish skin.
2 citations
,
October 2016 in “Nutrition in clinical practice” Vitamin B12 deficiency can cause facial dark spots that go away with treatment.
25 citations
,
May 1995 in “Journal of the American Academy of Dermatology” Erythromelanosis follicularis faciei can also affect women, though it's rare.
12 citations
,
November 2011 in “Pediatric dermatology” A 16-year-old boy had a rare case of Becker's nevus on his face and mouth.
The digital system for measuring melasma shows promise but needs more development for better accuracy and automation.
25 citations
,
December 2008 in “Journal of Dermatological Case Reports” Skin color may change how alopecia areata looks under a dermoscope.
12 citations
,
January 2013 in “Indian dermatology online journal” Dermatopathia pigmentosa reticularis causes skin discoloration, hair loss, and nail problems.
4 citations
,
May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
9 citations
,
September 2020 in “Journal of cosmetic dermatology” A woman developed vitiligo from repeated eyebrow microblading.
October 2022 in “Boletín médico del Hospital infantil de México/Boletín médico del Hospital Infantil de México” The patient has a rare skin condition that shows features of two known disorders.
18 citations
,
February 2001 in “Der Hautarzt” A woman with myotonic dystrophy had multiple skin tumors on her scalp, suggesting a genetic link.
10 citations
,
June 2009 in “Acta Biochimica Polonica” Old C57BL/6 mice with unsynchronized hair cycles show less melanin in their spleens.
Melanocyte transplantation can safely restore skin color, especially in stable vitiligo, but must be chosen carefully based on the disease phase.
7 citations
,
July 2017 in “Australasian Journal of Dermatology” Reflectance confocal microscopy is useful for diagnosing scalp melanomas, which have features similar to those on the trunk.
26 citations
,
June 2004 in “Clinical Genetics” The keratin 5 mutation in a family with epidermolysis bullosa simplex was due to mosaicism, not a new mutation.
1 citations
,
October 2022 in “Dermatology practical & conceptual” Isolated patchy heterochromia with pili annulati can occur without other health issues.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” A 73-year-old woman with Hypopigmented Mycosis Fungoides, a rare skin lymphoma, experienced disease progression despite treatment, emphasizing the need for ongoing monitoring.
9 citations
,
July 2010 in “British Journal of Dermatology” The document suggests a rare skin condition might be caused by a genetic phenomenon.
31 citations
,
April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
30 citations
,
May 2019 in “Journal of the European Academy of Dermatology and Venereology”
April 2019 in “Journal of Investigative Dermatology” The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.
2 citations
,
September 2022 The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.
April 2024 in “The Indonesian Biomedical Journal” Melanocyte stem cells from non-affected skin in vitiligo patients can become functional melanocytes for potential therapy.
1 citations
,
December 2018 in “IOP conference series. Materials science and engineering” CD34+ hair follicle stem cells can become melanin-producing cells for treating skin conditions.
44 citations
,
April 1979 in “Journal of Ultrastructure Research”
15 citations
,
January 2000 in “Dermatology” Minoxidil use may cause skin pigmentation loss.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.
2 citations
,
August 2008 in “Oncotarget” Apoptosis in hair follicles spreads through cell death signals, with stem cells slowing the process.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of early-stage melanocytes is reduced in vitiligo-affected skin, which may explain treatment resistance.